Clopidogrel or Prasugrel reduces mortality and lessens cardiovascular damage from acute myocardial infarction in Hypercholesterolemic male rats.
Sign Up to like & getrecommendations! Published in 2020 at "Life sciences"
DOI: 10.1016/j.lfs.2020.117429
Abstract: AIMS Hypercholesterolemia is a hazard for increasing susceptibility of the heart to myocardial infarction (MI) by inducing platelet hyperaggregability. Clopidogrel and prasugrel have documented cardioprotective effects in clinical studies. Herein, we investigated whether clopidogrel and… read more here.
Keywords: clopidogrel prasugrel; hypercholesterolemic rats; myocardial infarction;
Insights from In Vitro and Clinical Data to Guide Transition from the Novel P2Y12 Antagonist Selatogrel to Clopidogrel, Prasugrel, and Ticagrelor.
Sign Up to like & getrecommendations! Published in 2021 at "Thrombosis and haemostasis"
DOI: 10.1055/s-0040-1721773
Abstract: Reduced pharmacodynamic (PD) effects of irreversible oral P2Y12 receptor antagonists have been reported when administered during cangrelor infusion. Therefore, the PD interaction liability of the novel P2Y12 receptor antagonist selatogrel with irreversible (i.e., clopidogrel, prasugrel)… read more here.
Keywords: ticagrelor; clopidogrel prasugrel; novel p2y12; selatogrel ... See more keywords