Association Between Environmental Factors and Toxigenic Clostridioides difficile Carriage at Hospital Admission
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DOI: 10.1001/jamanetworkopen.2019.19132
Abstract: Key Points Question Is an individual’s location of residence associated with asymptomatic carriage of toxigenic Clostridiodes difficile? Findings In this cohort study of 3043 adult participants admitted to the hospital, patients who lived closer to… read more here.
Keywords: hospital admission; environmental factors; association environmental; clostridioides difficile ... See more keywords
Incidence and Outcomes Associated With Clostridioides difficile Infection in Solid Organ Transplant Recipients
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DOI: 10.1001/jamanetworkopen.2021.41089
Abstract: Key Points Question What are the incidence and outcomes associated with posttransplant Clostridioides difficile infection (CDI) in people who have undergone solid organ transplant? Findings In this cohort study including 10 724 patients, posttransplant CDI was… read more here.
Keywords: outcomes associated; organ transplant; clostridioides difficile; incidence outcomes ... See more keywords
Assessment of Quality of Life Among Patients With Recurrent Clostridioides difficile Infection Treated with Investigational Oral Microbiome Therapeutic SER-109
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DOI: 10.1001/jamanetworkopen.2022.53570
Abstract: This secondary analysis of a randomized clinical trial examines the association of SER-109 with health-related quality of life in 182 patients with recurrent Clostridioides difficile infection in the US and Canada. read more here.
Keywords: recurrent clostridioides; clostridioides difficile; difficile infection; patients recurrent ... See more keywords
Safety and Tolerability of SER-109 as an Investigational Microbiome Therapeutic in Adults With Recurrent Clostridioides difficile Infection
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DOI: 10.1001/jamanetworkopen.2022.55758
Abstract: This phase 3, open-label, single-arm trial assesses the safety of SER-109 and the rate of recurrent Clostridioides difficile infection after administration of SER-109 following symptom resolution after antibiotic treatment among adults. read more here.
Keywords: recurrent clostridioides; safety; clostridioides difficile; difficile infection ... See more keywords
Synthesis of Muramyl‐δ‐Lactam in Spore Peptidoglycan of Clostridioides difficile
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DOI: 10.1002/cbic.202300282
Abstract: Clostridioides difficile is a spore‐forming human pathogen responsible for significant morbidity and mortality. Infections by this pathogen ensue dysbiosis of the intestinal tract, which leads to germination of the spores. The process of spore formation… read more here.
Keywords: clostridioides difficile; muramyl lactam; lactam spore; synthesis muramyl ... See more keywords
Molecular epidemiology and clinical characteristics of Clostridioides difficile infection in patients with inflammatory bowel disease from a teaching hospital
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.24773
Abstract: Clostridioides difficile infection (CDI) in patients with inflammatory bowel disease (IBD) is of increasing concern. This study aimed to investigate the molecular epidemiology and antimicrobial susceptibilities of toxigenic C. difficile isolated from IBD patients and… read more here.
Keywords: clostridioides difficile; patients inflammatory; inflammatory bowel; difficile infection ... See more keywords
Higher mortality rates associated with Clostridioides difficile infection in hospitalized children with cystic fibrosis
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DOI: 10.1002/ppul.26214
Abstract: To determine the association of Clostridioides difficile Infection (CDI) with in‐hospital mortality, Length of Stay (LOS), and hospital charges among pediatric Cystic Fibrosis (CF) hospitalizations using a large nationally representative pediatric hospital database. read more here.
Keywords: cystic fibrosis; clostridioides difficile; mortality; difficile infection ... See more keywords
Performance of commercial PCR assays to detect toxigenic Clostridioides difficile in the feces of puppies
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DOI: 10.1002/vms3.567
Abstract: Abstract Clostridioides difficile is an important enteric pathogen that causes significant morbidity and mortality in humans. With community‐acquired infections on the rise, it is important to identify reservoirs of the pathogen. Companion animals can be… read more here.
Keywords: clostridioides difficile; predictive values; performance commercial; commercial pcr ... See more keywords
Metabolic Labeling of Clostridioides difficile Proteins.
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DOI: 10.1007/978-1-0716-1024-4_19
Abstract: The introduction of stable isotopes in vivo via metabolic labeling approaches (SILAC or 15N-labeling) allows, after combination of differentially treated labeled and unlabeled cells or protein extracts, for correction of protein quantification errors implemented during… read more here.
Keywords: clostridioides difficile; labeling clostridioides; biology; metabolic labeling ... See more keywords
Absence of Toxemia in Clostridioides difficile Infection: Results from Ultrasensitive Toxin Assay of Serum
Sign Up to like & getrecommendations! Published in 2020 at "Digestive Diseases and Sciences"
DOI: 10.1007/s10620-020-06683-8
Abstract: Clostridioides difficile infection (CDI) is caused by Toxins A and B, secreted from pathogenic strains of C. difficle. This infection can vary greatly in symptom severity and in clinical presentation. Current assays used to diagnose… read more here.
Keywords: difficile infection; clostridioides difficile; infection; serum ... See more keywords
Clostridioides difficile colonization and infection in patients with newly diagnosed acute leukemia: Incidence, risk factors, and patient outcomes.
Sign Up to like & getrecommendations! Published in 2019 at "American journal of infection control"
DOI: 10.1016/j.ajic.2018.09.027
Abstract: BACKGROUND The frequency, risk factors, and outcomes for Clostridioides difficile infection (CDI) in patients with newly diagnosed acute leukemia (AL) admitted for induction therapy are unclear. METHODS We studied 509 consecutive patients with AL admitted… read more here.
Keywords: risk; cdi; clostridioides difficile; infection ... See more keywords