Transgenic plants expressing a Clostridium difficile spore antigen as an approach to develop low‐cost oral vaccines
Sign Up to like & getrecommendations! Published in 2021 at "Biotechnology Progress"
DOI: 10.1002/btpr.3141
Abstract: Gastrointestinal infections caused by Clostridium difficile lead to significant impact in terms of morbidity and mortality, causing from mild symptoms, such as a low‐grade fever, watery stools, and minor abdominal cramping as well as more… read more here.
Keywords: clostridium difficile; ltb cdem; oral vaccines; low cost ... See more keywords
2,4‐Disubstituted 5‐Nitroimidazoles Potent against Clostridium difficile
Sign Up to like & getrecommendations! Published in 2019 at "ChemMedChem"
DOI: 10.1002/cmdc.201800784
Abstract: Metronidazole is one of the first‐line treatments for non‐severe Clostridium difficile infections (CDI). However, resistance limits its use in cases of severe and complicated CDI. Structure–activity relationships previously described for the 5‐nitroimidazole series have shown… read more here.
Keywords: clostridium difficile; difficile; nitroimidazoles potent; potent clostridium ... See more keywords
Receptors and Binding Structures for Clostridium difficile Toxins A and B.
Sign Up to like & getrecommendations! Published in 2017 at "Current topics in microbiology and immunology"
DOI: 10.1007/82_2016_17
Abstract: Two characteristics of toxins A and B from C. difficile (TcdA, TcdB) are important for the understanding of the pathogenic effect of these homologous toxins. First, these toxins are huge single-chain but multidomain proteins that… read more here.
Keywords: clostridium difficile; structures clostridium; receptors binding; binding structures ... See more keywords
Immunization Strategies Against Clostridium difficile.
Sign Up to like & getrecommendations! Published in 2018 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-3-319-72799-8_12
Abstract: C. difficile infection (CDI) is an important healthcare- but also community-associated disease. CDI is considered a public health threat and an economic burden. A major problem is the high rate of recurrences. Besides classical antibiotic… read more here.
Keywords: clostridium difficile; strategies clostridium; immunization; target ... See more keywords
Clostridium difficile, the Difficult “Kloster” Fuelled by Antibiotics
Sign Up to like & getrecommendations! Published in 2018 at "Current Microbiology"
DOI: 10.1007/s00284-018-1543-8
Abstract: Clostridium difficile is normally present in low numbers in a healthy adult gastro-intestinal tract (GIT). Drastic changes in the microbial population, e.g., dysbiosis caused by extensive treatment with antibiotics, stimulates the growth of resistant strains… read more here.
Keywords: clostridium difficile; difficult kloster; difficile; difficile difficult ... See more keywords
Prevalence of Clostridium difficile isolated from various raw meats in Korea
Sign Up to like & getrecommendations! Published in 2018 at "Food Science and Biotechnology"
DOI: 10.1007/s10068-018-0318-0
Abstract: Clostridium difficile is an anaerobic, toxin-producing pathogen that causes human infection possibly through the consumption of meat. Clostridium difficile was isolated from 45 of 415 (10.8%) various raw meat samples collected in nationwide markets in… read more here.
Keywords: difficile isolated; clostridium difficile; difficile; raw meats ... See more keywords
A comparison of air sampling methods for Clostridium difficile endospore aerosol
Sign Up to like & getrecommendations! Published in 2019 at "Aerobiologia"
DOI: 10.1007/s10453-019-09566-2
Abstract: The airborne dissemination of Clostridium difficile (C. difficile) endospores (spores) in healthcare environments is documented in multiple studies. Once airborne, spores have the potential for transport on air currents to other areas. This study compared… read more here.
Keywords: clostridium difficile; airborne spores; sampling methods; difficile ... See more keywords
Outcomes of Fecal Microbiota Transplantation for Clostridium difficile Infection in Patients with Inflammatory Bowel Disease
Sign Up to like & getrecommendations! Published in 2017 at "Digestive Diseases and Sciences"
DOI: 10.1007/s10620-017-4580-4
Abstract: Background and AimsFecal microbiota transplantation (FMT) has recently been shown to be a promising therapy for recurrent and refractory Clostridium difficile infections (CDI) despite lack of protocol standardization. Patients with inflammatory bowel disease (IBD) present… read more here.
Keywords: clostridium difficile; microbiota transplantation; patients inflammatory;
Fecal Transplantation for Treatment of Clostridium Difficile Infection in Elderly and Debilitated Patients
Sign Up to like & getrecommendations! Published in 2017 at "Digestive Diseases and Sciences"
DOI: 10.1007/s10620-017-4833-2
Abstract: BackgroundFecal microbiota transplantation (FMT) is a new technique recently introduced to treat recurrent Clostridium difficile infection (CDI). Little is known about the efficacy and risks of FMT in elderly and ill patients.AimTo investigate FMT efficacy… read more here.
Keywords: clostridium difficile; difficile infection; treatment; group ... See more keywords
Association of Household Pets, Common Dietary Factors, and Lifestyle Factors with Clostridium difficile Infection
Sign Up to like & getrecommendations! Published in 2020 at "Digestive Diseases and Sciences"
DOI: 10.1007/s10620-020-06123-7
Abstract: Background Clostridium difficile infection (CDI) is one of the most common hospital-acquired infections and is associated with significant morbidity and mortality. Since owning a cat or dog could enrich the gut microbiome, we hypothesized that… read more here.
Keywords: clostridium difficile; cdi; cdi testing; difficile infection ... See more keywords
Evolving Strategies to Manage Clostridium difficile Colitis
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Gastrointestinal Surgery"
DOI: 10.1007/s11605-019-04478-5
Abstract: Clostridium difficile infection remains a common nosocomial illness with a significant impact on health care delivery. As molecular phenotyping of this organism has changed our understanding of its transmission and virulence, so too have diagnostic… read more here.
Keywords: clostridium difficile; infection; clostridium; evolving strategies ... See more keywords