Structural and biochemical characterization of Clostridium perfringens pili protein B collagen‐binding domains
Sign Up to like & getrecommendations! Published in 2023 at "FEBS Letters"
DOI: 10.1002/1873-3468.14626
Abstract: Sortase‐mediated pili are flexible rod proteins composed of major and minor/tip pilins, playing important roles in the initial adhesion of bacterial cells to host tissues. The pilus shaft is formed by covalent polymerization of major… read more here.
Keywords: collagen; binding domains; tip; clostridium perfringens ... See more keywords
Evaluation of the preventive and therapeutic effects of a recombinant vector co‐expressing prostate‐specific stem cell antigen and Clostridium perfringens enterotoxin on prostate cancer in rats
Sign Up to like & getrecommendations! Published in 2019 at "Biotechnology Progress"
DOI: 10.1002/btpr.2906
Abstract: The effects of Clostridium perfringens enterotoxin (CPE) and prostate stem cell antigen (PSCA) on cancer prevention or treatment have been previously studied separately. For the first time, here we have elaborated a recombinant vector to… read more here.
Keywords: prostate; vector; clostridium perfringens; stem cell ... See more keywords
Recombinant Limosilactobacillus (Lactobacillus) delivering nanobodies against Clostridium perfringens NetB and alpha toxin confers potential protection from necrotic enteritis
Sign Up to like & getrecommendations! Published in 2022 at "MicrobiologyOpen"
DOI: 10.1002/mbo3.1270
Abstract: Necrotic enteritis (NE), caused by Clostridium perfringens, is an intestinal disease with devastating economic losses to the poultry industry. NE is a complex disease and predisposing factors that compromise gut integrity are required to facilitate… read more here.
Keywords: limosilactobacillus lactobacillus; necrotic enteritis; clostridium perfringens; toxin ... See more keywords
Synthesis, 18F-labelling and radiopharmacological characterisation of the C-terminal 30mer of Clostridium perfringens enterotoxin as a potential claudin-targeting peptide
Sign Up to like & getrecommendations! Published in 2018 at "Amino Acids"
DOI: 10.1007/s00726-018-2657-9
Abstract: The cell surface receptor claudin-4 (Cld-4) is upregulated in various tumours and represents an important emerging target for both diagnosis and treatment of solid tumours of epithelial origin. The C-terminal fragment of the Clostridium perfringens… read more here.
Keywords: peptide; cld; claudin; clostridium perfringens ... See more keywords
Effect of continuous sub-culturing on infectivity of Clostridium perfringens ATCC13124 in mouse gas gangrene model
Sign Up to like & getrecommendations! Published in 2017 at "Folia Microbiologica"
DOI: 10.1007/s12223-017-0503-1
Abstract: Clostridium perfringens is a Validated Biological Agent and a pathogen of medical, veterinary, and military significance. Gas gangrene is the most destructive of all the clostridial diseases and is caused by C. perfringens type A… read more here.
Keywords: clostridium perfringens; gas gangrene; infectivity; gas ... See more keywords
Exposure to β-lactams results in the alteration of penicillin-binding proteins in Clostridium perfringens.
Sign Up to like & getrecommendations! Published in 2017 at "Anaerobe"
DOI: 10.1016/j.anaerobe.2017.02.004
Abstract: Clostridium perfringens causes a variety of mild to severe infections in humans and other animals. A decrease in the affinity of penicillin-binding protein (PBP) transpeptidases for β-lactams is considered one of the mechanisms of β-lactam… read more here.
Keywords: clostridium perfringens; exposure lactams; penicillin; lactams results ... See more keywords
Clostridium perfringens - A bacterial pathogen gaining recognition in necrotizing pancreatitis.
Sign Up to like & getrecommendations! Published in 2017 at "Anaerobe"
DOI: 10.1016/j.anaerobe.2017.05.006
Abstract: We report an interesting case of necrotizing pancreatitis due to Clostridium perfringens in an elderly man who came to the hospital with complaints of severe abdominal pain. The infection further worsened with the dissemination to… read more here.
Keywords: pancreatitis; clostridium perfringens; necrotizing pancreatitis; perfringens bacterial ... See more keywords
X-ray structure of Clostridium perfringens sortase B cysteine transpeptidase.
Sign Up to like & getrecommendations! Published in 2017 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2017.09.144
Abstract: The pathogenesis and infectivity of Gram-positive bacteria are mediated by many surface proteins that are covalently attached to peptidoglycans of the cell wall. The covalent attachment of these proteins is catalyzed by sortases (Srts), a… read more here.
Keywords: sortase cysteine; perfringens sortase; clostridium perfringens; clostridium ... See more keywords
Structural and biochemical characterization of the Clostridium perfringens-specific Zn2+-dependent amidase endolysin, Psa, catalytic domain.
Sign Up to like & getrecommendations! Published in 2021 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2021.08.085
Abstract: Phage-derived endolysins, enzymes that degrade peptidoglycans, have the potential to serve as alternative antimicrobial agents. Psa, which was identified as an endolysin encoded in the genome of Clostridium perfringens st13, was shown to specifically lyse… read more here.
Keywords: psa catalytic; catalytic domain; clostridium perfringens; amidase ... See more keywords
MicroRNA-21-5p targets PDCD4 to modulate apoptosis and inflammatory response to Clostridium perfringens beta2 toxin infection in IPEC-J2 cells.
Sign Up to like & getrecommendations! Published in 2020 at "Developmental and comparative immunology"
DOI: 10.1016/j.dci.2020.103849
Abstract: Clostridium perfringens (C. perfringens), a toxin-producing enteric pathogen, causes a variety of intestinal infections in humans and animals. C. perfringens beta2 (CPB2) toxin has been considered to be a strong virulence factor for C. perfringens… read more here.
Keywords: response; apoptosis; clostridium perfringens; ipec cells ... See more keywords
A survey of a blown pack spoilage produced by Clostridium perfringens in vacuum-packaged wurstel.
Sign Up to like & getrecommendations! Published in 2021 at "Food microbiology"
DOI: 10.1016/j.fm.2020.103654
Abstract: Three hundred Clostridium strains were isolated from spoiled wurstels and were identified by traditional and molecular methods as Clostridium perfringens. The phenotypic characteristics of the strains were studied. All the strains produced acetic and butyric… read more here.
Keywords: spoilage; clostridium perfringens; clostridium; survey blown ... See more keywords