Biomimetic Microgels with Controllable Deformability Improve Healing Outcomes
Sign Up to like & getrecommendations! Published in 2018 at "Advanced Biosystems"
DOI: 10.1002/adbi.201800042
Abstract: Platelets mediate hemostasis by aggregating and binding to fibrin to promote clotting. Over time, platelets contract the fibrin network to induce clot retraction, which contributes to wound healing outcomes by increasing clot stability and improving… read more here.
Keywords: clot; clot retraction; degrees shell; healing outcomes ... See more keywords
Imaging the dynamics and microstructure of fibrin clot polymerization in cardiac surgical patients using spectrally encoded confocal microscopy
Sign Up to like & getrecommendations! Published in 2021 at "American Journal of Hematology"
DOI: 10.1002/ajh.26217
Abstract: During cardiac surgery with cardiopulmonary bypass (CPB), altered hemostatic balance may disrupt fibrin assembly, predisposing patients to perioperative hemorrhage. We investigated the utility of a novel device termed spectrally‐encoded confocal microscopy (SECM) for assessing fibrin… read more here.
Keywords: clot; fibrin clot; microscopy; spectrally encoded ... See more keywords
Quantification of bone marrow plasma cell infiltration in multiple myeloma: usefulness of bone marrow aspirate clot with CD138 immunohistochemistry
Sign Up to like & getrecommendations! Published in 2017 at "Hematological Oncology"
DOI: 10.1002/hon.2300
Abstract: Accurate quantification of plasma cells (PCs) in bone marrow (BM) is critical for diagnosis and assessment of treatment response in patients with multiple myeloma (MM). We compared the % of BM PC quantified by 250… read more here.
Keywords: clot; biopsy; cd138; bone marrow ... See more keywords
Bone marrow aspirate clot: A technical complication or a smart approach for musculoskeletal tissue regeneration?
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.26065
Abstract: One of the methods employed to improve healing of damaged tissues is the use of cellular based therapies. A number of regenerative medicine based strategies, from in vitro expanded mesenchymal stem cells (MSCs) to “one‐step”… read more here.
Keywords: clot; bma; regeneration; aspirate ... See more keywords
Dimensional evaluation of blood clot gap distances within intrabony defects following grafting and EDTA root surface treatment—experimental study in dogs
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Periodontology"
DOI: 10.1002/jper.17-0361
Abstract: BACKGROUND Because it is important to establish and maintain a firm blood clot to the surrounding tissues within the intrabony lesion; we have to investigate the potentials of different materials in resisting clot retraction that… read more here.
Keywords: clot; gap; root surface; group ... See more keywords
Evaluating blood clot progression using magnetic particle spectroscopy
Sign Up to like & getrecommendations! Published in 2018 at "Medical Physics"
DOI: 10.1002/mp.12983
Abstract: Purpose To evaluate the thrombus maturity noninvasively providing the promise of much earlier and more accurate diagnosis of diseases ranging from stroke to myocardial infarction to deep vein thrombosis. Methods Magnetic spectroscopy of nanoparticle Brownian… read more here.
Keywords: clot; relaxation time; blood; spectroscopy ... See more keywords
Clinical Cellular Therapeutics Accelerate Clot Formation
Sign Up to like & getrecommendations! Published in 2018 at "Stem Cells Translational Medicine"
DOI: 10.1002/sctm.18-0015
Abstract: Clinical cellular therapeutics (CCTs) have shown preliminary efficacy in reducing inflammation after trauma, preserving cardiac function after myocardial infarction, and improving functional recovery after stroke. However, most clinically available cell lines express tissue factor (TF)… read more here.
Keywords: clot; medicine; cellular therapeutics; clinical cellular ... See more keywords
Quantitative Characterization of Recanalization and Distal Emboli with a Novel Thrombectomy Device
Sign Up to like & getrecommendations! Published in 2020 at "CardioVascular and Interventional Radiology"
DOI: 10.1007/s00270-020-02683-3
Abstract: Purpose The first-pass effect during mechanical thrombectomy improves clinical outcomes regardless of first-line treatment approach, but current success rates for complete clot capture with one attempt are still less than 40%. We hypothesize that the… read more here.
Keywords: clot; recanalization; distal emboli; retriever ... See more keywords
A new compressible hyperelastic model for the multi-axial deformation of blood clot occlusions in vessels.
Sign Up to like & getrecommendations! Published in 2021 at "Biomechanics and modeling in mechanobiology"
DOI: 10.1007/s10237-021-01446-4
Abstract: Mechanical thrombectomy can be significantly affected by the mechanical properties of the occluding thrombus. In this study, we provide the first characterisation of the volumetric behaviour of blood clots. We propose a new hyperelastic model… read more here.
Keywords: clot; hyperelastic model; deformation; blood ... See more keywords
Designing a multifunctional staphylokinase variant (SAK-2RGD-TTI) with appropriate thrombolytic activity in vitro
Sign Up to like & getrecommendations! Published in 2019 at "Biotechnology Letters"
DOI: 10.1007/s10529-019-02748-5
Abstract: Objective Thrombin, platelets, and plasmin are three key factors involved in hemostasis and thrombolysis. Thrombolytic therapy with clinically approved drugs is often followed by recurrent thrombosis caused by thrombin-induced platelet aggregation from the clot debris.… read more here.
Keywords: clot; 2rgd tti; staphylokinase; designing multifunctional ... See more keywords
COVID-19 associated coagulopathy in critically ill patients: A hypercoagulable state demonstrated by parameters of haemostasis and clot waveform analysis
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Thrombosis and Thrombolysis"
DOI: 10.1007/s11239-020-02318-x
Abstract: Patients with COVID-19 are known to be at risk of developing both venous, arterial and microvascular thrombosis, due to an excessive immuno-thrombogenic response to the SARS-CoV-2 infection. Overlapping syndromes of COVID-19 associated coagulopathy with consumptive… read more here.
Keywords: clot; iqr; ill patients; associated coagulopathy ... See more keywords