Clot-Targeted Antithrombotic Liposomal Nanomedicine Containing High Content of H2O2-Activatable Hybrid Prodrugs.
Sign Up to like & getrecommendations! Published in 2023 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.2c20750
Abstract: Liposomes have been extensively explored as drug carriers, but their clinical translation has been hampered by their low drug-loading content and premature leakage of drug payloads. It was reasoned that vesicle-forming prodrugs could be incorporated… read more here.
Keywords: antithrombotic liposomal; clot targeted; targeted antithrombotic; liposomal nanomedicine ... See more keywords
Clot‐targeted magnetic hyperthermia permeabilizes blood clots to make them more susceptible to thrombolysis
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Thrombosis and Haemostasis"
DOI: 10.1111/jth.15846
Abstract: Thrombolysis is a frontline treatment for stroke, which involves the application of tissue plasminogen activator (tPA) to trigger endogenous clot‐degradation pathways. However, it is only effective within 4.5 h of symptom onset because of clot… read more here.
Keywords: thrombolysis; clot; targeted magnetic; clot targeted ... See more keywords