Articles with "clozapine levels" as a keyword



T203. RELEVANT CLOZAPINE BLOOD LEVELS USING A POINT OF CARE TEST (POCT)

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Published in 2020 at "Schizophrenia Bulletin"

DOI: 10.1093/schbul/sbaa029.763

Abstract: Abstract Background Clozapine is one of the most underused medications in psychiatry for many reasons including mandatory blood testing, fear of serious side-effects, lack of patient adherence. A critical barrier to adoption could be addressed… read more here.

Keywords: clozapine; point care; poct; clozapine levels ... See more keywords

F224. UTILITY OF SALIVA FOR MONITORING OF CLOZAPINE LEVELS

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Published in 2018 at "Schizophrenia Bulletin"

DOI: 10.1093/schbul/sby017.755

Abstract: Abstract Background Clozapine has specific indication for use in Treatment Resistant Schizophrenia (TRS) with guidelines for therapeutic drug monitoring. Though a plasma level > 350 ng/ml has been cited as the therapeutic threshold, many other… read more here.

Keywords: plasma; saliva; clozapine; monitoring clozapine ... See more keywords

Association between electroencephalogram changes and plasma clozapine levels in clozapine-treated patients

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Published in 2019 at "International Clinical Psychopharmacology"

DOI: 10.1097/yic.0000000000000255

Abstract: This retrospective observational study was performed to investigate electroencephalogram abnormalities in clozapine-treated patients with refractory schizophrenia or bipolar disorder. The electroencephalogram and plasma clozapine and norclozapine levels in 71 patients were measured on the same… read more here.

Keywords: clozapine; clozapine levels; electroencephalogram abnormalities; clozapine treated ... See more keywords

A Double-edged Sword: Balancing the Benefits and Risks of Clozapine

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Published in 2025 at "BJPsych Open"

DOI: 10.1192/bjo.2025.10770

Abstract: Aims: Clozapine is recommended for treatment-resistant schizophrenia after two other antipsychotics have failed. We discuss a case of clozapine toxicity on therapeutic dose and its complications due to multifactorial causes. Methods: 60 years Caucasian female,… read more here.

Keywords: double edged; clozapine; edged sword; toxicity ... See more keywords

Influence of dose, gender, and cigarette smoking on clozapine plasma concentrations

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Published in 2018 at "Neuropsychiatric Disease and Treatment"

DOI: 10.2147/ndt.s163839

Abstract: Introduction Therapeutic drug monitoring (TDM) of clozapine is a very useful method for verifying both the correct intake and the interindividual variability of its metabolism, thereby avoiding the risk of toxicity. The purposes of this… read more here.

Keywords: gender cigarette; clozapine; gender; cigarette smoking ... See more keywords