Clozapine Response in Schizophrenia and Hematological Changes
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DOI: 10.1097/jcp.0000000000001329
Abstract: Abstract Background Clozapine is the only effective medication for treatment-resistant schizophrenia; however, its mechanism of action remains unclear. The present study explored whether its effectiveness is related to changes in hematological measures after clozapine initiation.… read more here.
Keywords: response; treatment; hematological changes; clozapine response ... See more keywords
Genetic determinants associated with response to clozapine in schizophrenia: an umbrella review
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DOI: 10.1097/ypg.0000000000000320
Abstract: Objective Clozapine response varies widely from person to person, which may be due to inter-individual genetic variability. This umbrella review aims to summarize the current evidence on associations between pharmacodynamic genes and response to clozapine… read more here.
Keywords: clozapine response; genetic determinants; response clozapine; clozapine ... See more keywords
Biological Predictors of Clozapine Response: A Systematic Review
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DOI: 10.3389/fpsyt.2018.00327
Abstract: Background: Clozapine is the recommended antipsychotic for treatment-resistant schizophrenia (TRS) but there is significant variability between patients in the degree to which clozapine will improve symptoms. The biological basis of this variability is unknown. Although… read more here.
Keywords: clozapine; response; clozapine response; review ... See more keywords