Investigating the renoprotective effect of C21 in male mice with sepsis via modulation of p-AKT/PI3K expression
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Medicine and Life"
DOI: 10.25122/jml-2022-0299
Abstract: This study aimed to investigate if C21 could prevent acute renal injury induced by sepsis by regulating the expression of p-AKT/PI3K. Five equal groups of 25 adult male Swiss-albino mice were randomly divided (n=5): sham… read more here.
Keywords: clp; pi3k expression; clp group; group ... See more keywords
Alprostadil alleviates liver injury in septic rats via TLR4/NF-κB pathway.
Sign Up to like & getrecommendations! Published in 2021 at "European review for medical and pharmacological sciences"
DOI: 10.26355/eurrev_202102_24869
Abstract: OBJECTIVE The aim of this study was to explore the role of alprostadil (Alp) in cecal ligation and puncture (CLP)-induced septic injury in rats and its possible mechanism of action. MATERIALS AND METHODS Wistar rats… read more here.
Keywords: tlr4 pathway; group; liver; clp group ... See more keywords
Neutrophil phenotypes implicated in the pathophysiology of post-traumatic sepsis
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Medicine"
DOI: 10.3389/fmed.2022.982399
Abstract: Background The disruption of immune homeostasis after trauma is a major cause of post-traumatic organ dysfunction and/or sepsis. Recently, a variety of neutrophil phenotypes with distinct functions have been identified and suggested as involved in… read more here.
Keywords: sepsis; burn clp; clp group; neutrophil phenotypes ... See more keywords
[Hydrogen plays a protective role in intestinal injury of mice with severe sepsis by regulating the release of heme oxygenase-1 and high mobility group protein B1].
Sign Up to like & getrecommendations! Published in 2020 at "Zhonghua wei zhong bing ji jiu yi xue"
DOI: 10.3760/cma.j.cn121430-20200717-00533
Abstract: OBJECTIVE To investigate the protective effect of the hydrogen (H2) inhalation on intestinal injury in severe sepsis mice and its relationship with nuclear factor E2-related factor 2 (Nrf2)/heme oxygenase-1 (HO-1)/high mobility group protein B1 (HMGB1)… read more here.
Keywords: hmgb1; group; clp group; expression ... See more keywords
[Analysis of the changes in intestinal microecology in the early stage of sepsis rat based on 16S rDNA sequencing].
Sign Up to like & getrecommendations! Published in 2022 at "Zhonghua wei zhong bing ji jiu yi xue"
DOI: 10.3760/cma.j.cn121430-20201215-00754
Abstract: OBJECTIVE To investigate the changes of intestinal microecology in the early stage of sepsis rat model by 16S rDNA sequencing. METHODS Sixty male Sprague-Dawley (SD) rats were randomly divided into cecal ligation and puncture (CLP)… read more here.
Keywords: analysis; group; sepsis; changes intestinal ... See more keywords
[Effect and mechanism of Rho kinase inhibitor on intestinal injury in septic rats].
Sign Up to like & getrecommendations! Published in 2022 at "Zhonghua wei zhong bing ji jiu yi xue"
DOI: 10.3760/cma.j.cn121430-20210923-01392
Abstract: OBJECTIVE To explore the effect of Rho kinase inhibitor on intestinal injury in septic rats and its possible mechanism. METHODS Thirty-two male Sprague-Dawley (SD) rats were randomly divided into sham operation group (Sham group), Rho… read more here.
Keywords: group; sham group; intestinal injury; clp group ... See more keywords
[Effects of hydrogen on lung injury in wild-type and Nrf2 gene knockout mice: relationship with Nrf2/HO-1/HMGB1 pathway].
Sign Up to like & getrecommendations! Published in 2019 at "Zhonghua wei zhong bing ji jiu yi xue"
DOI: 10.3760/cma.j.issn.2095-4352.2019.07.013
Abstract: OBJECTIVE To investigate the key role of nuclear factor E2-related factor 2 (Nrf2) in the treatment of lung injury in sepsis mice by regulating Nrf2/heme oxygenase-1 (HO-1)/high mobility group protein B1 (HMGB1) pathway. METHODS 120… read more here.
Keywords: group; clp group; sham group; mice ... See more keywords