Impact of Hindlimb Disuse on Sepsis-Induced Myopathy in Older Adult Mice
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DOI: 10.1152/physiol.2024.39.s1.1495
Abstract: BACKGROUND: Sepsis, a life-threatening condition due to an overactive immune response, adversely affects multiple organ systems. Despite its significance of accounting for 40% of total body mass, the skeletal muscle system is considered the forgotten… read more here.
Keywords: physiology; muscle; clp hls; sepsis ... See more keywords
Delayed muscle recovery post disuse in older septic mice
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DOI: 10.1152/physiol.2025.40.s1.1133
Abstract: Background: Sepsis, a life-threatening overreactive response of the immune system to an infection, is predominant in the older population (>65 years of age). Advances in intensive care therapies have improved survival rates, resulting in an… read more here.
Keywords: mice; physiology; clp; muscle ... See more keywords
The impact of hindlimb disuse on sepsis‐induced myopathy in mice
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DOI: 10.14814/phy2.14979
Abstract: Sepsis induces a myopathy characterized by loss of muscle mass and weakness. Septic patients undergo prolonged periods of limb muscle disuse due to bed rest. The contribution of limb muscle disuse to the myopathy phenotype… read more here.
Keywords: sepsis; muscle; clp hls; disuse ... See more keywords