Antibody-dependent cellular cytotoxicity targeting CD4-inducible epitopes predicts mortality in HIV-infected infants
Sign Up to like & getrecommendations! Published in 2019 at "EBioMedicine"
DOI: 10.1016/j.ebiom.2019.08.072
Abstract: Background Antibody-dependent cellular cytotoxicity (ADCC) has been associated with improved infant outcome in mother-to-child transmission (MTCT) of HIV-1. Epitopes of these ADCC-mediating antibodies remain unidentified. CD4-inducible (CD4i) epitopes on gp120 are common ADCC targets in… read more here.
Keywords: adcc; infant survival; cluster specific; antibody dependent ... See more keywords
A molecular taxonomy of tumors independent of tissue-of-origin
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DOI: 10.7490/f1000research.1118501.1
Abstract: Abstract Cancer is a complex disease involving disrupted cellular metabolism, basic biochemical processes, and the microenvironment. However, despite some generally agreed upon unifying principles (Hanahan and Weinberg 2000, 2011), molecular signatures remain largely indistinguishable from… read more here.
Keywords: tissue origin; tissue specific; biology; tissue ... See more keywords