Toll-like receptor 4 signaling is required for clusterin-induced tumor necrosis factor-α secretion in macrophage.
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DOI: 10.1016/j.bbrc.2016.12.049
Abstract: Clusterin is a secretory glycoprotein that is up-regulated in areas of inflammation and under increased levels of oxidative stress. Previously, we demonstrated that clusterin activates NF-κB, and up-regulates the expression of MMP-9 and TNF-α. In… read more here.
Keywords: secretion; clusterin; macrophage; clusterin induced ... See more keywords