Clustering of NLRP3 induced by membrane or protein scaffolds promotes inflammasome assembly
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DOI: 10.1038/s41467-025-60277-4
Abstract: NLRP3 is a pattern recognition receptor forming an inflammasome in response to diverse pathogen and self-derived triggers, but molecular insights on NLRP3 activation are still lacking. Here, we drive ectopic NLRP3 to different subcellular locations… read more here.
Keywords: clustering nlrp3; activation; protein; nlrp3 variants ... See more keywords