Stable and sustained release liposomal formulations of celecoxib: In vitro and in vivo anti-tumor evaluation.
Sign Up to like & getrecommendations! Published in 2018 at "International journal of pharmaceutics"
DOI: 10.1016/j.ijpharm.2018.01.039
Abstract: Celecoxib (CLX) is a selective COX-2 inhibitor with anticancer potential in a COX-2 dependent and independent manner. CLX's low water solubility has a dose limiting effect on its utilization in cancer treatment. Here, we developed… read more here.
Keywords: tumor; vivo; clx; anti tumor ... See more keywords
Boesenbergia rotunda (L.) Mansf. extract potentiates the antibacterial activity of some β-lactams against β-lactam-resistant staphylococci.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of global antimicrobial resistance"
DOI: 10.1016/j.jgar.2017.10.019
Abstract: OBJECTIVES The purpose of this study was to investigate the effect of Boesenbergia rotunda (L.) Mansf. extract (BRE) and peptidoglycan inhibitor antibiotics, alone and in combination, against β-lactam-resistant staphylococci. METHODS Antibacterial and synergistic activities of… read more here.
Keywords: rotunda mansf; boesenbergia rotunda; resistant staphylococci; clx ... See more keywords
Biodegradation of cefalexin by two bacteria strains from sewage sludge
Sign Up to like & getrecommendations! Published in 2023 at "Royal Society Open Science"
DOI: 10.1098/rsos.220442
Abstract: Bioremediation has been used as an environmentally-friendly, energy-saving and efficient method for removing pollutants. However, there have been very few studies focusing on the specific antibiotic-degrading microorganisms in the activated sludge and their degradation mechanism.… read more here.
Keywords: two bacteria; cefalexin; cefalexin two; biodegradation ... See more keywords
Enhanced Oral Bioavailability of Celecoxib Nanocrystalline Solid Dispersion based on Wet Media Milling Technique: Formulation, Optimization and In Vitro/In Vivo Evaluation
Sign Up to like & getrecommendations! Published in 2019 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics11070328
Abstract: Celecoxib (CLX), a selective COX-2 inhibitor, is a biopharmaceutics classification system (BCS) class II drug with its bioavailability being limited by thepoor aqueoussolubility. The purpose of this study was to develop and optimize CLX nanocrystalline(CLX-NC)… read more here.
Keywords: oral bioavailability; celecoxib; solid dispersion; clx ... See more keywords