Manipulating Active Structure and Function of Cationic Antimicrobial Peptide CM15 with the Polysulfonated Drug Suramin: A Step Closer to in Vivo Complexity
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DOI: 10.1002/cbic.201800801
Abstract: Antimicrobial peptides (AMPs) kill bacteria by targeting their membranes through various mechanisms involving peptide assembly, often coupled with disorder‐to‐order structural transition. However, for several AMPs, similar conformational changes in cases in which small organic compounds… read more here.
Keywords: peptide; drug; cm15; function ... See more keywords
A novel simple experimental model for low-osmolar contrast-induced acute kidney injury using different definitions based on the levels of serum creatinine and cystatin C
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DOI: 10.1186/s12882-019-1436-5
Abstract: BackgroundIt remained lack of a kind of contrast-induced acute kidney injury (CI-AKI) model which was widely used in clinical practice and comparable to CI-AKI in humans.MethodsFifty Sprague-Dawley rats were divided into five groups of 10… read more here.
Keywords: contrast; group; contrast induced; model ... See more keywords
Molecular Dynamics Simulation of Antimicrobial Peptide CM15 in Staphylococcus Aureus and Escherichia coli Model Bilayer Lipid
Sign Up to like & getrecommendations! Published in 2023 at "Iranian Journal of Biotechnology"
DOI: 10.30498/ijb.2023.337246.3344
Abstract: Background: In animals and plants, antimicrobial peptides (AMPs) are crucial components of defense mechanisms, as they play a crucial role in innate immunity, which protects hosts from pathogenic bacteria. The CM15 has attracted considerable interest… read more here.
Keywords: escherichia coli; aureus escherichia; molecular dynamics; staphylococcus aureus ... See more keywords