Articles with "cmg oxaliplatin" as a keyword



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Abstract C014: Development of an injectable water-soluble anticancer drug CMG for oxaliplatin-resistant colorectal cancer with KRAS mutation

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Published in 2019 at "Molecular Cancer Therapeutics"

DOI: 10.1158/1535-7163.targ-19-c014

Abstract: Recent well-designed preclinical studies have demonstrated that KRAS mutations can activate the canonical NF-κB signaling pathway, which is a pivotal role in tumor progression. Therefore, inhibition of this KRAS-NF-κB axis would be a promising target… read more here.

Keywords: cancer; water soluble; cmg oxaliplatin; colorectal cancer ... See more keywords