Arginine substitution by alanine at the P1 position increases the selectivity of CmPI-II, a non-classical Kazal inhibitor
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DOI: 10.1016/j.bbrep.2021.101008
Abstract: CmPI-II is a Kazal-type tight-binding inhibitor isolated from the Caribbean snail Cenchritis muricatus. This inhibitor has an unusual specificity in the Kazal family, as it can inhibit subtilisin A (SUBTA), elastases and trypsin. An alanine… read more here.
Keywords: alanine; inhibitor; inhibition; site ... See more keywords