CMTM3 overexpression promotes cell apoptosis while DHT promotes cell proliferation in hair follicle stem cells (HFSCs).
Sign Up to like & getrecommendations! Published in 2020 at "Genomics"
DOI: 10.1016/j.ygeno.2020.12.029
Abstract: In Yangtze River Delta white goat, hypermethylation of CMTM3 leads to a decreased expression level in high quality brush hair. However, the regulation of CMTM3 expression and its function in hair follicle stem cells (HFSCs)… read more here.
Keywords: hair follicle; follicle stem; proliferation; cmtm3 ... See more keywords
CMTM3 as a Potential New Immune Checkpoint Regulator
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Oncology"
DOI: 10.1155/2022/2103515
Abstract: Objectives To evaluate the role of CKLF-like MARVEL transmembrane domain containing 3 (CMTM3) in tumor microenvironment and cancer immunotherapy and explore its potential mechanism. Method The cancer genome map was obtained from the UCSC Xena… read more here.
Keywords: cmtm3 potential; cmtm3; genes immune; cmtm3 expression ... See more keywords
miR-135b-5p promotes gastric cancer progression by targeting CMTM3.
Sign Up to like & getrecommendations! Published in 2018 at "International journal of oncology"
DOI: 10.3892/ijo.2017.4222
Abstract: CKLF-like MARVEL transmembrane domain containing 3 (CMTM3) is considered to be a tumor suppressor gene in multiple types of malignancies. Previous studies have indicated that CMTM3 suppresses metastasis and epithelial-mesenchymal transition (EMT) in gastric cancer. However,… read more here.
Keywords: gastric cancer; cmtm3; mir 135b; progression ... See more keywords