Persistent primary cytomegalovirus infection in a kidney transplant recipient: Multi-drug resistant and compartmentalized infection leading to graft loss.
Sign Up to like & getrecommendations! Published in 2019 at "Antiviral research"
DOI: 10.1016/j.antiviral.2019.06.004
Abstract: Cytomegalovirus (CMV) is one of the most common opportunistic infections after transplantation. To prevent CMV infections, universal prophylaxis and pre-emptive therapy with ganciclovir or its prodrug valganciclovir is applied. However, prolonged antiviral therapy may result… read more here.
Keywords: cmv; cmv disease; infection; drug ... See more keywords
Determination of Optimal Viral Kinetic Markers for Predicting Antiviral Treatment Effect for the Prevention of Cytomegalovirus (CMV) Disease after Hematopoietic Cell Transplant (HCT) Using Machine Learning and a Novel Non-Parametric Estimation Method
Sign Up to like & getrecommendations! Published in 2019 at "Biology of Blood and Marrow Transplantation"
DOI: 10.1016/j.bbmt.2018.12.559
Abstract: The United States Food and Drug Administration recently issued guidance that CMV DNAemia (quantitative CMV viral load as measured by PCR) could be used in a composite endpoint along with tissue-invasive CMV disease as the… read more here.
Keywords: cmv disease; treatment; cmv; viral load ... See more keywords
Incidence and Impact of Cytomegalovirus in Hematopoietic Cell Transplant Recipients at a Single Center over the Last Decade
Sign Up to like & getrecommendations! Published in 2020 at "Biology of Blood and Marrow Transplantation"
DOI: 10.1016/j.bbmt.2019.12.381
Abstract: Objective CMV continues to have a significant impact on HCT despite preemptive antiviral (PET) strategies. Our objective was to assess the incidence and impact of CMV in HCT recipients. Methods We performed a retrospective analysis… read more here.
Keywords: impact; cmv; cmv disease; incidence impact ... See more keywords
A Novel Cytomegalovirus Prophylaxis Protocol in Cytomegalovirus (CMV) D+/R- Heart Transplant Recipients: A Single-Center Experience
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cardiac Failure"
DOI: 10.1016/j.cardfail.2018.07.450
Abstract: Background We previously reported that after completion of 3 months of prophylactic treatment with valganciclovir in cytomegalovirus (CMV) donor positive, recipient negative (D+/R-) heart transplant patients, there was a high incidence of CMV disease, with… read more here.
Keywords: cmv; heart; cmv disease; cytomegalovirus ... See more keywords
Multicenter study on recent portal venous system thrombosis associated with cytomegalovirus disease.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of hepatology"
DOI: 10.1016/j.jhep.2021.09.011
Abstract: BACKGROUND AND AIMS Recent non-malignant non-cirrhotic portal venous system thrombosis (PVT) is a rare condition. Among risk factors for PVT, cytomegalovirus (CMV) disease is usually listed based on few reported cases. The aim of this… read more here.
Keywords: cmv; cmv disease; venous system; portal venous ... See more keywords
CMV seronegative donors: Effect on clinical severity of CMV infection and reconstitution of CMV-specific immunity.
Sign Up to like & getrecommendations! Published in 2018 at "Transplant immunology"
DOI: 10.1016/j.trim.2018.04.003
Abstract: BACKGROUND Cytomegalovirus (CMV)-specific T-cells are crucial to prevent CMV disease. CMV seropositive recipients transplanted with stem cells from a CMV seronegative allogeneic donor (R+D-) may be at risk for CMV disease due to absence of… read more here.
Keywords: cmv; cmv disease; cmv seronegative; cmv specific ... See more keywords
Progressive, Long-Term Hearing Loss in Congenital CMV Disease After Ganciclovir Therapy.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of the Pediatric Infectious Diseases Society"
DOI: 10.1093/jpids/piab095
Abstract: BACKGROUND Long-term hearing outcomes among children with symptomatic congenital cytomegalovirus (CMV) disease who received 6-week ganciclovir therapy early in life are unknown. METHODS Longitudinal study of 76 children with symptomatic congenital CMV disease, born 1983-2005,… read more here.
Keywords: term hearing; cmv disease; long term; group ... See more keywords
1569. Incidence, Risk Factors, and Impact of Antiviral Prophylaxis Duration on Cytomegalovirus (CMV) Disease in High-Risk Donor Seropositive/Recipient Seronegative [D+R−] Orthotopic Heart Transplant Recipients (OHTR)
Sign Up to like & getrecommendations! Published in 2018 at "Open Forum Infectious Diseases"
DOI: 10.1093/ofid/ofy210.1397
Abstract: Abstract Background CMV disease is a major cause of morbidity and mortality in OHTR, especially among D+R− patients. Clinical trials of longer antiviral prophylaxis have shown reduced CMV disease incidence in kidney and lung transplant… read more here.
Keywords: risk; cmv disease; antiviral prophylaxis; disease ... See more keywords
CMV infection and management among pediatric solid organ transplant recipients.
Sign Up to like & getrecommendations! Published in 2022 at "Pediatric transplantation"
DOI: 10.1111/petr.14220
Abstract: BACKGROUND Cytomegalovirus (CMV) is an important cause of morbidity and mortality in pediatric solid organ transplant (SOT) recipients. However, the impact of asymptomatic CMV infections (ie, DNAemia) on clinical outcomes is not well established. METHODS… read more here.
Keywords: cmv dnaemia; prophylaxis; disease; cmv disease ... See more keywords
Association of Cytomegalovirus Diseases with Newly Developed Myocardial Infarction and Congestive Heart Failure: Data from a National Population-based Cohort
Sign Up to like & getrecommendations! Published in 2021 at "Archives of Medical Science"
DOI: 10.5114/aoms/105157
Abstract: Introduction Anti-cytomegalovirus (CMV) IgG seropositive and/or titer are associated with a higher risk of cardiovascular diseases (CVD). However, it is not clear whether CMV end-organ disease may have relation to development of CVD or chronic… read more here.
Keywords: cmv disease; infarction congestive; heart; cohort ... See more keywords