A Single Center Experience of Letermovir for the Prevention of CMV Infection in CMV-Seropositive Allogeneic Cell Transplant (Allo-HCT) Recipients
Sign Up to like & getrecommendations! Published in 2019 at "Biology of Blood and Marrow Transplantation"
DOI: 10.1016/j.bbmt.2018.12.339
Abstract: Introduction and Objectives Letermovir (LTV) is the first agent in the class of anti-CMV viral terminase inhibitors and was recently approved in the U.S. for the prevention of CMV infection in CMV-seropositive allo-HCT recipients. In… read more here.
Keywords: allo hct; cmv seropositive; hct recipients; cmv ... See more keywords
Latent CMV makes older adults less naïve
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DOI: 10.1016/j.ebiom.2022.103887
Abstract: eBioMedicine 2022;77: 103887 Published online xxx https://doi.org/10.1016/j. ebiom.2022.103887 There is a widespread general consensus that protective immunity against infectious disease in older people is less effective than in younger adults, due to “immunosenescence”. There has… read more here.
Keywords: older adults; cmv seropositive; cd4 cells; latent cmv ... See more keywords
Cytomegalovirus infection in HIV-infected and uninfected individuals is characterized by circulating regulatory T cells of unconstrained antigenic specificity
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DOI: 10.1371/journal.pone.0180691
Abstract: Cytomegalovirus (CMV) infection is associated with immune-suppression in immune-compromised hosts and old adults. We previously showed that ex vivo CMV restimulation of peripheral blood mononuclear cells (PBMC) of CMV-seropositive volunteers expanded CD4+CD27-CD28- regulatory T cells… read more here.
Keywords: cd27 cd28; cmv seropositive; cd27; cd4 cd27 ... See more keywords