Isolation, characterization, and expression of proto-oncogene cMyc in large yellow croaker Larimichthys crocea
Sign Up to like & getrecommendations! Published in 2017 at "Fish Physiology and Biochemistry"
DOI: 10.1007/s10695-017-0384-x
Abstract: AbstractcMyc is a vital transcription factor that involves in the regulation of cell proliferation, growth, differentiation, and apoptosis. In the present study, cMyc in Larimichthys crocea (Lc-cMyc) was cloned and analyzed for investigating its function.… read more here.
Keywords: cell stage; larimichthys crocea; expression; cmyc ... See more keywords
Implication of connexin30 on the stemness of glioma: connexin30 reverses the malignant phenotype of glioma by modulating IGF-1R, CD133 and cMyc
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Neuro-Oncology"
DOI: 10.1007/s11060-017-2608-4
Abstract: Gap-junctional intercellular communication (GJIC) plays a major role in the malignant growth of glioma. Although the mechanistic aspects of GJIC have been extensively studied, the role of connexins in the regulation of the malignant behavior… read more here.
Keywords: cd133 cmyc; connexin30; glioma; cmyc ... See more keywords
Peroxisome proliferator‐activated receptor &ggr; activation inhibits liver growth through miR‐122‐mediated downregulation of cMyc
Sign Up to like & getrecommendations! Published in 2017 at "European Journal of Pharmacology"
DOI: 10.1016/j.ejphar.2017.01.016
Abstract: Abstract Although NR1C3 agonists inhibit cell growth, the molecular mechanism of their action has not been thoroughly characterized to date. A recent study demonstrated that NR1C3 can regulate miR‐122 by binding to its promoter. Given… read more here.
Keywords: mir 122; downregulation; activation; cmyc ... See more keywords
Loss of MYSM1 inhibits the oncogenic activity of cMYC in B cell lymphoma
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DOI: 10.1111/jcmm.16554
Abstract: MYSM1 is a chromatin‐binding protein, widely investigated for its functions in haematopoiesis in human and mouse; however, its role in haematologic malignancies remains unexplored. Here, we investigate the cross‐talk between MYSM1 and oncogenic cMYC in… read more here.
Keywords: mysm1; cmyc; loss mysm1; cell lymphoma ... See more keywords
Abstract 1459: Nanocage delivered engineered destabilized 3UTR ARE of cMYC inhibits triple negative breast cancer growth and metastasis in vivo by targeting cMYC and downregulating STAT5A5B
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-1459
Abstract: c-MYC is a master transcription factor overexpressed in more than 70% of human cancers including breast cancers (TNBC), lung cancers, brain tumors, prostate cancers, lymphomas, pediatrics cancers, pancreatic cancers, colorectal cancers, and ovarian cancers. Yet… read more here.
Keywords: metastasis; vivo; breast; triple negative ... See more keywords
Abstract 3941: CRISPR screen of human stem cell derived MYC-driven medulloblastoma tumors reveal the mitochondria as a vulnerability
Sign Up to like & getrecommendations! Published in 2025 at "Cancer Research"
DOI: 10.1158/1538-7445.am2025-3941
Abstract: Medulloblastoma (MB) is the most common malignant pediatric brain tumor and is derived from neuroepithelial stem cells (NESC). Amplification of each member of the MYC family of oncogenes (MYCN, CMYC, MYCL) has been found in… read more here.
Keywords: stem cell; mycn cmyc; cmyc;
Role of HNF4alpha-cMyc interaction in liver regeneration after partial hepatectomy
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DOI: 10.3389/fendo.2024.1404318
Abstract: Background Hepatocyte nuclear factor 4 alpha (HNF4α) is the master regulator of hepatic differentiation. Recent studies have also revealed the role of HNF4α in hepatocyte proliferation via negatively regulating the expression of proto-mitogenic genes, including… read more here.
Keywords: hnf4 cmyc; hnf4; liver regeneration; cmyc ... See more keywords
Characterization of unique B-cell populations in the circulation of people living with HIV prior to non-Hodgkin lymphoma diagnosis
Sign Up to like & getrecommendations! Published in 2024 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2024.1441994
Abstract: People living with HIV (PLWH) are at higher risk of developing lymphoma. In this study, we performed cytometry by time-of-flight (CyTOF) on peripheral blood mononuclear cells of cART-naïve HIV+ individuals and cART-naïve HIV+ individuals prior… read more here.
Keywords: cart; pre; cxcr4; cell ... See more keywords
Low-level expression of Cmyc in mature neurons: maintaining neuronal function and preventing neurodegeneration.
Sign Up to like & getrecommendations! Published in 2025 at "Neural regeneration research"
DOI: 10.4103/nrr.nrr-d-24-01367
Abstract: ABSTRACT Cmyc, a proto-oncogene, is expressed at extremely low levels in mature neurons and is traditionally thought to have no function in these cells. However, recent studies suggest that Cmyc may play a crucial role… read more here.
Keywords: disease; function; dopaminergic neurons; mature neurons ... See more keywords