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   Articles with "cmyc" as a keyword



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Isolation, characterization, and expression of proto-oncogene cMyc in large yellow croaker Larimichthys crocea

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recommendations! Published in 2017 at "Fish Physiology and Biochemistry"

DOI: 10.1007/s10695-017-0384-x

Abstract: AbstractcMyc is a vital transcription factor that involves in the regulation of cell proliferation, growth, differentiation, and apoptosis. In the present study, cMyc in Larimichthys crocea (Lc-cMyc) was cloned and analyzed for investigating its function.… read more here.

Keywords: cell stage; larimichthys crocea; expression; cmyc ... See more keywords

Implication of connexin30 on the stemness of glioma: connexin30 reverses the malignant phenotype of glioma by modulating IGF-1R, CD133 and cMyc

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recommendations! Published in 2017 at "Journal of Neuro-Oncology"

DOI: 10.1007/s11060-017-2608-4

Abstract: Gap-junctional intercellular communication (GJIC) plays a major role in the malignant growth of glioma. Although the mechanistic aspects of GJIC have been extensively studied, the role of connexins in the regulation of the malignant behavior… read more here.

Keywords: cd133 cmyc; connexin30; glioma; cmyc ... See more keywords
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Peroxisome proliferator‐activated receptor &ggr; activation inhibits liver growth through miR‐122‐mediated downregulation of cMyc

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recommendations! Published in 2017 at "European Journal of Pharmacology"

DOI: 10.1016/j.ejphar.2017.01.016

Abstract: Abstract Although NR1C3 agonists inhibit cell growth, the molecular mechanism of their action has not been thoroughly characterized to date. A recent study demonstrated that NR1C3 can regulate miR‐122 by binding to its promoter. Given… read more here.

Keywords: mir 122; downregulation; activation; cmyc ... See more keywords
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Loss of MYSM1 inhibits the oncogenic activity of cMYC in B cell lymphoma

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recommendations! Published in 2021 at "Journal of Cellular and Molecular Medicine"

DOI: 10.1111/jcmm.16554

Abstract: MYSM1 is a chromatin‐binding protein, widely investigated for its functions in haematopoiesis in human and mouse; however, its role in haematologic malignancies remains unexplored. Here, we investigate the cross‐talk between MYSM1 and oncogenic cMYC in… read more here.

Keywords: mysm1; cmyc; loss mysm1; cell lymphoma ... See more keywords
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Abstract 1459: Nanocage delivered engineered destabilized 3UTR ARE of cMYC inhibits triple negative breast cancer growth and metastasis in vivo by targeting cMYC and downregulating STAT5A5B

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recommendations! Published in 2023 at "Cancer Research"

DOI: 10.1158/1538-7445.am2023-1459

Abstract: c-MYC is a master transcription factor overexpressed in more than 70% of human cancers including breast cancers (TNBC), lung cancers, brain tumors, prostate cancers, lymphomas, pediatrics cancers, pancreatic cancers, colorectal cancers, and ovarian cancers. Yet… read more here.

Keywords: metastasis; vivo; breast; triple negative ... See more keywords