The CnB1 p.D102A variant is linked to dilated cardiomyopathy via impaired Calcineurin activity.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of molecular and cellular cardiology"
DOI: 10.1016/j.yjmcc.2020.08.012
Abstract: BACKGROUND The role of calcineurin (protein phosphatase 2B (PP2B)) in the pathogenesis of human dilated cardiomyopathy (DCM) has not been fully elucidated. We determined the potential involvement of calcineurin in the pathogenesis of DCM caused… read more here.
Keywords: calcineurin activity; cnb1; calcineurin; variant ... See more keywords