Articles with "cncc" as a keyword



FOXO acts as a positive regulator of CncC and deltamethrin tolerance in the red flour beetle, Tribolium castaneum.

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Published in 2022 at "Pest management science"

DOI: 10.1002/ps.6811

Abstract: BACKGROUND Both forkhead box O (FOXO) and nuclear factor erythroid-derived 2-like-2 (Nrf2) are key transcription factors related to stress response. While limited studies in mammals and Caenorhabditis elegans revealed interaction between FoxO/DAF-16 and Nrf2/SKN-1, the… read more here.

Keywords: cncc; tribolium castaneum; deltamethrin; foxo ... See more keywords

Three cytochrome P450 CYP4 family genes regulated by the CncC signaling pathway mediate phytochemical susceptibility in the red flour beetle, Tribolium castaneum.

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Published in 2022 at "Pest management science"

DOI: 10.1002/ps.6991

Abstract: BACKGROUND Insect cytochrome P450 monooxygenases (P450s) play a crucial role in phytochemical metabolism and tolerance. Three P450 genes (TcCYP4Q3, TcCYP4Q5, TcCYP4Q7) are associated with the response of eugenol in Tribolium castaneum. However, the responding mechanisms… read more here.

Keywords: signaling pathway; cncc signaling; p450 genes; cncc ... See more keywords

PI3K/Akt/CncC signaling pathway mediates response to EPN-Bt infection in Holotrichia parallela larvae.

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Published in 2022 at "Pest management science"

DOI: 10.1002/ps.7337

Abstract: BACKGROUND Combining the entomopathogenic nematode (EPN), Heterorhabditis beicherriana LF strain and Bacillus thuringiensis (Bt) HBF-18 strain is a practical strategy to manage the larvae of Holotrichia parallela Motschulsky (white grubs). However, the mechanisms underlying the… read more here.

Keywords: pi3k; pi3k akt; cncc; epn infection ... See more keywords
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Activation of CncC pathway is involved in the regulation of P450 genes responsible for clothianidin resistance in Bradysia odoriphaga.

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Published in 2023 at "Pest management science"

DOI: 10.1002/ps.7482

Abstract: BACKGROUND Insect cytochrome P450 monooxygenases (P450s) play a key role in the detoxification metabolism of insecticides and their overexpression is often associated with insecticide resistance. Our previous research showed that the overexpression of four P450… read more here.

Keywords: clothianidin resistance; clothianidin; cncc; expression ... See more keywords

Activation of CncC pathway by ROS burst regulates cytochrome P450 CYP6AB12 responsible for λ-cyhalothrin tolerance in Spodoptera litura.

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Published in 2019 at "Journal of hazardous materials"

DOI: 10.1016/j.jhazmat.2019.121698

Abstract: Frequent insecticide use poses an environmental hazard and also selects for insecticide tolerance. Increased metabolic detoxification by cytochrome P450 monooxygenases (P450s) is the most common mechanism of insecticide tolerance. However, the underlying regulatory mechanisms remain… read more here.

Keywords: tolerance; cyp6ab12; cncc; cytochrome p450 ... See more keywords

hReg-CNCC reconstructs a regulatory network in human cranial neural crest cells and annotates variants in a developmental context

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Published in 2021 at "Communications Biology"

DOI: 10.1038/s42003-021-01970-0

Abstract: Cranial Neural Crest Cells (CNCC) originate at the cephalic region from forebrain, midbrain and hindbrain, migrate into the developing craniofacial region, and subsequently differentiate into multiple cell types. The entire specification, delamination, migration, and differentiation… read more here.

Keywords: network; hreg cncc; cncc; neural crest ... See more keywords
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The pleiotropic AMPK-CncC signaling pathway regulates the trade-off between detoxification and reproduction.

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Published in 2023 at "Proceedings of the National Academy of Sciences of the United States of America"

DOI: 10.1073/pnas.2214038120

Abstract: The association of decreased fecundity with insecticide resistance and the negative sublethal effects of insecticides on insect reproduction indicates the typical trade-off between two highly energy-demanding processes, detoxification and reproduction. However, the underlying mechanisms are… read more here.

Keywords: detoxification reproduction; cncc; ampk cncc; reproduction ... See more keywords

Interplay between autophagy and CncC regulates dendrite pruning in Drosophila

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Published in 2024 at "Proceedings of the National Academy of Sciences of the United States of America"

DOI: 10.1073/pnas.2310740121

Abstract: Significance Autophagy clears damaged organelles and long-lived proteins in eukaryotic cells including neurons. However, whether and how autophagy regulates elimination of neuronal processes during development remain poorly understood. Here, we report an important role of… read more here.

Keywords: autophagy cncc; dendrite pruning; cncc; cncc regulates ... See more keywords

Evaluating the Association of Calcified Neurocysticercosis and Mesial Temporal Lobe Epilepsy With Hippocampal Sclerosis in a Large Cohort of Patients With Epilepsy

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Published in 2022 at "Frontiers in Neurology"

DOI: 10.3389/fneur.2021.769356

Abstract: Background Neurocysticercosis (NCC) is a parasitic infection of the central nervous system that has been associated with mesial temporal lobe epilepsy with hippocampal sclerosis (MTLE-HS). However, this association has not been completely established. Objective To… read more here.

Keywords: mesial temporal; patients epilepsy; cncc; cohort ... See more keywords