Pyruvate dehydrogenase subunit β of Lactobacillus plantarum is a collagen adhesin involved in biofilm formation
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Basic Microbiology"
DOI: 10.1002/jobm.201600575
Abstract: Multi‐functional surface proteins have been observed in a variety of pathogenic bacteria, where they mediate host cell adhesion and invasion, as well as in commensal bacterial species, were they mediate positive interaction with the host.… read more here.
Keywords: collagen; cni; lactobacillus plantarum; pyruvate dehydrogenase ... See more keywords
YB-1 increases glomerular, but decreases interstitial fibrosis in CNI-induced nephropathy.
Sign Up to like & getrecommendations! Published in 2018 at "Clinical immunology"
DOI: 10.1016/j.clim.2018.07.002
Abstract: Calcineurin inhibitors (CNIs) are a cornerstone of the current treatment in solid organ transplantation and autoimmune disease. However, CNIs also bear deleterious effects as they cause glomerular and tubulointerstitial fibrosis in the kidney. We recently… read more here.
Keywords: cni; fibrosis; increases glomerular; glomerular decreases ... See more keywords
Calcineurin Inhibitors With Reduced-Dose Steroids as First-Line Therapy for Focal Segmental Glomerulosclerosis
Sign Up to like & getrecommendations! Published in 2019 at "Kidney International Reports"
DOI: 10.1016/j.ekir.2018.08.010
Abstract: Introduction High-dose corticosteroids remain the first-line therapy for focal and segmental glomerulosclerosis (FSGS), whereas calcineurin inhibitors (CNIs) are reserved for those patients resistant to corticosteroid therapy. Methods This is a retrospective cohort analysis in patients… read more here.
Keywords: cni; line; first line; high dose ... See more keywords
Facile synthesis of high nitrogen-doped content, mesopore-dominated biomass-derived hierarchical porous graphitic carbon for high performance supercapacitors
Sign Up to like & getrecommendations! Published in 2020 at "Electrochimica Acta"
DOI: 10.1016/j.electacta.2020.135615
Abstract: Abstract Design and preparation of high N-doped content biomass-derived hierarchical porous carbon with appropriate pores size distribution and high electrical conductivity draw extensive research attention for supercapacitors. Herein, N-doped mesopore-dominated hierarchical porous graphitic carbons PG/PEI-CNi… read more here.
Keywords: mesopore dominated; cni; doped content; hierarchical porous ... See more keywords
Nasal irrigation with Glycyrrhiza glabra extract for treatment of allergic rhinitis - A study of in vitro, in vivo and clinical trial.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of ethnopharmacology"
DOI: 10.1016/j.jep.2021.114116
Abstract: ETHNOPHARMACOLOGICAL RELEVANCE Glycyrrhiza glabra, a family of licorice and a traditional Chinese medicine with sweet taste and favorable smell, has anti-inflammatory, anti-allergic and immunomodulatory functions. AIM OF THE STUDY We developed a licorice extract (LE)… read more here.
Keywords: allergic rhinitis; cni; trial; irrigation ... See more keywords
Efficacy and safety profile of calcineurin inhibitor salvage therapy in autoimmune hepatitis
Sign Up to like & getrecommendations! Published in 2020 at "Scandinavian Journal of Gastroenterology"
DOI: 10.1080/00365521.2020.1821764
Abstract: Abstract Background As data is limited on the outcomes of calcineurin inhibitors (CNI) in autoimmune hepatitis (AIH), we evaluated the efficacy and safety of CNI in AIH patients who failed prior treatment(s). Methods A retrospective… read more here.
Keywords: cni; autoimmune hepatitis; efficacy safety; treatment ... See more keywords
An update on chemical pharmacotherapy options for the prevention of kidney transplant rejection with a focus on costimulation blockade
Sign Up to like & getrecommendations! Published in 2017 at "Expert Opinion on Pharmacotherapy"
DOI: 10.1080/14656566.2017.1323876
Abstract: ABSTRACT Introduction: The introduction of calcineurin inhibitors (CNI) has greatly improved graft survival in the past three decades. However, long-term graft survival is still limited due to chronic allograft injury and side-effects of immunosuppressive medication.… read more here.
Keywords: cni; focus; rejection; transplantation ... See more keywords
The Analysis of Pathological and Serological Findings in the Long-Term Pediatric Liver Transplantation: The Achievement of Clinical Operational Tolerance
Sign Up to like & getrecommendations! Published in 2018 at "Transplantation"
DOI: 10.1097/01.tp.0000543991.95051.81
Abstract: Introduction Clinical operational tolerance can be achieved after liver transplantation in some proportion of selected patients. We have tried to reduce immunosuppression (IS) of the stable out-patient pediatric liver transplant recipients. In this cross-sectional study,… read more here.
Keywords: cni; fibrosis; operational tolerance; tolerance ... See more keywords
Everolimus Initiation With Early Calcineurin Inhibitor Withdrawal in De Novo Heart Transplant Recipients: Long-term Follow-up From the Randomized SCHEDULE Study
Sign Up to like & getrecommendations! Published in 2019 at "Transplantation"
DOI: 10.1097/tp.0000000000002702
Abstract: Supplemental Digital Content is available in the text. Background. A calcineurin inhibitor (CNI)-free immunosuppressive regimen has been demonstrated to improve renal function early after heart transplantation, but long-term outcome of such a strategy has not… read more here.
Keywords: novo heart; heart; cni; long term ... See more keywords
Mammalian target of rapamycin inhibitors combined with calcineurin inhibitors as initial immunosuppression in renal transplantation: a meta-analysis.
Sign Up to like & getrecommendations! Published in 2019 at "Transplantation"
DOI: 10.1097/tp.0000000000002769
Abstract: BACKGROUND The current standard of care immunosuppressive regimen in kidney transplantation (KT) includes a combination of mycophenolates (MMF/MPA) with a calcineurin inhibitor (CNI). METHODS We designed a systematic review including all randomized clinical trials (RCTs)… read more here.
Keywords: mtori cni; cni; transplantation; mmf mpa ... See more keywords
High Calcineurin Inhibitor Intrapatient Variability Is Associated With Renal Allograft Inflammation, Chronicity, and Graft Loss
Sign Up to like & getrecommendations! Published in 2019 at "Transplantation Direct"
DOI: 10.1097/txd.0000000000000862
Abstract: Background High calcineurin inhibitor (CNI) intrapatient variability (IPV) has been associated with poor kidney allograft outcomes. However, the relationship between early allograft histological changes, their progression, and CNI-IPV is less well studied. Hence, we evaluated… read more here.
Keywords: allograft; loss; cni ipv; cni ... See more keywords