Hereditary chronic neutrophilic leukemia in a four‐generation family without transformation to acute leukemia
Sign Up to like & getrecommendations! Published in 2024 at "American Journal of Hematology"
DOI: 10.1002/ajh.27420
Abstract: Chronic neutrophilic leukemia (CNL) is a rare myeloproliferative neoplasm (MPN) characterized by peripheral blood neutrophilia, marrow granulocyte hyperplasia, hepatosplenomegaly, and driver mutations in the colony‐stimulating factor 3 receptor (CSF3R). Designation of activating CSF3R mutations as… read more here.
Keywords: chronic neutrophilic; family; history; acute leukemia ... See more keywords
High‐performance N, P‐CNL nanocomposites as catalyst for oxygen reduction reaction in fuel cell
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Energy Research"
DOI: 10.1002/er.5280
Abstract: Transition metal and heteroatom codoped carbon materials have become the most promising materials to replace commercial platinum carbon (Pt / C) catalysts due to their low cost, high stability, and methanol resistance. In this work,… read more here.
Keywords: cnl; oxygen reduction; high performance;
Recent Progress in Chronic Neutrophilic Leukemia and Atypical Chronic Myeloid Leukemia
Sign Up to like & getrecommendations! Published in 2017 at "Current Hematologic Malignancy Reports"
DOI: 10.1007/s11899-017-0413-y
Abstract: Purpose of ReviewWe reviewed recent diagnostic and therapeutic progress in chronic neutrophilic leukemia (CNL) and atypical chronic myeloid leukemia (aCML). We summarized recent genetic data that may guide future efforts towards implementing risk-adapted therapy based… read more here.
Keywords: neutrophilic leukemia; progress chronic; myeloid; leukemia ... See more keywords
Role of Critical Nutrition Literacy in Making Informed Decisions About Dietary Behavior (OR08-07-19).
Sign Up to like & getrecommendations! Published in 2019 at "Current developments in nutrition"
DOI: 10.1093/cdn/nzz050.or08-07-19
Abstract: Objectives To determine if there is an association between critical nutrition literacy (CNL) and dietary behavior. It is hypothesized that college students with higher nutrition literacy scores will consume more fruits and vegetables (FV) and… read more here.
Keywords: literacy; critical nutrition; nutrition literacy; cnl ... See more keywords
Chronic neutrophilic leukemia, an extremely rare cause of neutrophilia in childhood: Cure with hematopoietic stem cell transplantation
Sign Up to like & getrecommendations! Published in 2018 at "Pediatric Transplantation"
DOI: 10.1111/petr.13199
Abstract: CNL is a rare myeloproliferative disorder frequently seen in older adults. A significant proportion of patients show progression to AML. Here, we report the case of a patient with FA who was monitored for leukopenia… read more here.
Keywords: transplantation chronic; neutrophilic leukemia; cure; chronic neutrophilic ... See more keywords
The PDI-ATF6-axis as a novel treatment target in CSF3R driven chronic neutrophilic leukemia (CNL)
Sign Up to like & getrecommendations! Published in 2025 at "Blood"
DOI: 10.1182/blood-2025-1453
Abstract: Introduction CNL is a rare myeloproliferative neoplasm (MPN) with a 5-year-survival-rate of 28 percent, and no standard of care for treatment. The majority of CNL patients harbors the membrane proximal T618I mutation in the colony-stimulating… read more here.
Keywords: csf3r; treatment; csf3rt618i; activation ... See more keywords
Coexisting of bone marrow fibrosis, dysplasia and an X chromosomal abnormality in chronic neutrophilic leukemia with CSF3R mutation: a case report and literature review
Sign Up to like & getrecommendations! Published in 2018 at "BMC Cancer"
DOI: 10.1186/s12885-018-4236-6
Abstract: BackgroundChronic neutrophilic leukemia (CNL) is a rare myeloproliferative neoplasm (MPN) with less than 40 cases of patients being reported or clinically suspected meeting with 2008 World Health Organization (“WHO”) diagnostic criteria. The current diagnosis of… read more here.
Keywords: marrow fibrosis; bone marrow; csf3r; mutation ... See more keywords
Comparing BRCA1/2 copy number loss assessment in circulating tumor DNA to tissue in advanced solid cancers.
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2025.43.16_suppl.e14545
Abstract: e14545 Background: Next generation sequencing (NGS) identifies genomic alterations in DNA obtained from tissue biopsies and/or blood [circulating tumor (ct)DNA]. We anticipate a lower rate of copy number loss (CNL) in ctDNA compared to tissue,… read more here.
Keywords: loss; brca1; ctdna; copy number ... See more keywords
Eighty-year-old man with rare chronic neutrophilic leukemia caused by CSF3R T618I mutation: A case report and review of literature
Sign Up to like & getrecommendations! Published in 2020 at "World Journal of Clinical Cases"
DOI: 10.12998/wjcc.v8.i24.6337
Abstract: BACKGROUND Chronic neutrophilic leukemia (CNL) is a rare bone marrow proliferative tumor and a heterogeneous disorder. In 2016, the World Health Organization included activating mutations in the CSF3R gene as one of the diagnostic criteria,… read more here.
Keywords: csf3r t618i; neutrophilic leukemia; year old; chronic neutrophilic ... See more keywords