A CCR4-NOT Transcription Complex, Subunit 1, CNOT1, Variant Associated with Holoprosencephaly.
Sign Up to like & getrecommendations! Published in 2019 at "American journal of human genetics"
DOI: 10.1016/j.ajhg.2019.03.017
Abstract: Holoprosencephaly is the incomplete separation of the forebrain during embryogenesis. Both genetic and environmental etiologies have been determined for holoprosencephaly; however, a genetic etiology is not found in most cases. In this report, we present… read more here.
Keywords: subunit cnot1; transcription complex; cnot1; ccr4 transcription ... See more keywords
CNOT1 regulates circadian behaviour through Per2 mRNA decay in a deadenylation-dependent manner
Sign Up to like & getrecommendations! Published in 2022 at "RNA Biology"
DOI: 10.1080/15476286.2022.2071026
Abstract: ABSTRACT Circadian clocks are an endogenous internal timekeeping mechanism that drives the rhythmic expression of genes, controlling the 24 h oscillatory pattern in behaviour and physiology. It has been recently shown that post-transcriptional mechanisms are… read more here.
Keywords: behaviour; per2 mrna; cnot1; expression ... See more keywords