Cnot8 eliminates naïve regulation networks and is essential for naïve-to-formative pluripotency transition
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DOI: 10.1093/nar/gkac236
Abstract: Abstract Mammalian early epiblasts at different phases are characterized by naïve, formative, and primed pluripotency states, involving extensive transcriptome changes. Here, we report that deadenylase Cnot8 of Ccr4-Not complex plays essential roles during the transition… read more here.
Keywords: cnot8 eliminates; pluripotency; regulation networks; cnot8 ... See more keywords