Computational prediction of CNP0387675 as a non-nucleoside inhibitor of MraY, from natural product-based multi-template screening against Pseudomonas aeruginosa
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DOI: 10.3389/fmicb.2025.1648850
Abstract: Antimicrobial resistance driven by multidrug-resistant Gram-negative bacteria, notably Pseudomonas aeruginosa, urgently necessitates novel antibacterial targets and inhibitors. MraY, an integral membrane enzyme catalyzing lipid I formation in peptidoglycan synthesis, represents an attractive antibacterial target. In… read more here.
Keywords: multi template; cnp0387675; non nucleoside; pseudomonas aeruginosa ... See more keywords