Cannabinoid receptor 1 signalling modulates stress susceptibility and microglial responses to chronic social defeat stress
Sign Up to like & getrecommendations! Published in 2021 at "Translational Psychiatry"
DOI: 10.1038/s41398-021-01283-0
Abstract: Psychosocial stress is one of the main environmental factors contributing to the development of psychiatric disorders. In humans and rodents, chronic stress is associated with elevated inflammatory responses, indicated by increased numbers of circulating myeloid… read more here.
Keywords: cnr1 mice; csds; cannabinoid receptor; stress ... See more keywords
Cannabinoid 1 receptor signaling on GABAergic neurons influences astrocytes in the ageing brain
Sign Up to like & getrecommendations! Published in 2018 at "PLoS ONE"
DOI: 10.1371/journal.pone.0202566
Abstract: Astrocytes, key regulators of brain homeostasis, interact with neighboring glial cells, neurons and the vasculature through complex processes involving different signaling pathways. It is not entirely clear how these interactions change in the ageing brain… read more here.
Keywords: gaba cnr1; cnr1 mice; ageing brain; brain ... See more keywords