Design, synthesis, computational and biological evaluation of new benzodiazepines as CNS agents
Sign Up to like & getrecommendations! Published in 2020 at "Arabian Journal of Chemistry"
DOI: 10.1016/j.arabjc.2017.08.005
Abstract: Abstract Two series of new benzodiazepines were synthesized and the target compounds (E1-10 and G1-10) were evaluated for antianxiety and skeletal muscle relaxant activity as CNS agents in albino mice. The chemical structures of the… read more here.
Keywords: new benzodiazepines; synthesis computational; cns agents; design synthesis ... See more keywords
Recent advances in the development of pyrimidine-based CNS agents.
Sign Up to like & getrecommendations! Published in 2022 at "Current drug discovery technologies"
DOI: 10.2174/1570163819666221003094402
Abstract: BACKGROUND In the past few decades, considerable progress has been made in CNS drug discovery, and various new CNS agents have been developed. Pyrimidine is an important scaffold in the area of medicinal chemistry. Recently,… read more here.
Keywords: based cns; development; cns; pyrimidine based ... See more keywords