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   Articles with "cns injuries" as a keyword



FTY720 in CNS injuries: Molecular mechanisms and therapeutic potential

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recommendations! Published in 2020 at "Brain Research Bulletin"

DOI: 10.1016/j.brainresbull.2020.08.013

Abstract: Central nervous system (CNS) injuries, such as traumatic brain injury (TBI), subarachnoid hemorrhage (SAH) and intracerebral hemorrhage (ICH), are important causes of disability and death worldwide. FTY720, a structural sphingosine analog and sphingosine-1-phosphate receptor (S1PR)… read more here.

Keywords: fty720 cns; fty720; injuries molecular; cns injuries ... See more keywords

Functional optic tract rewiring via subtype- and target-specific axonal regeneration and presynaptic activity enhancement

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recommendations! Published in 2025 at "Nature Communications"

DOI: 10.1038/s41467-025-57445-x

Abstract: Mechanisms underlying functional axonal rewiring after adult mammalian central nervous system (CNS) injuries remain unclear partially due to limited models. Here we develop a mouse intracranial pre–olivary pretectal nucleus (OPN) optic tract injury model and… read more here.

Keywords: presynaptic activity; cns injuries; optic tract; regeneration ... See more keywords

Advances in Optogenetics Applications for Central Nervous System Injuries.

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recommendations! Published in 2022 at "Journal of neurotrauma"

DOI: 10.1089/neu.2022.0290

Abstract: Injuries to the central nervous system (CNS) often lead to severe neurological dysfunction and even death. However, there are still no effective measures to improve functional recovery following CNS injuries. Optogenetics, an ideal method to… read more here.

Keywords: system; cns injuries; central nervous; advances optogenetics ... See more keywords

Systemic Immune Response to Traumatic CNS Injuries—Are Extracellular Vesicles the Missing Link?

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recommendations! Published in 2019 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2019.02723

Abstract: Inflammation following traumatic injury to the central nervous system (CNS) persists long after the primary insult and is known to exacerbate cell death and worsen functional outcomes. Therapeutic interventions targeting this inflammation have been unsuccessful,… read more here.

Keywords: extracellular vesicles; response; cns; systemic immune ... See more keywords

Circular RNA in Acute Central Nervous System Injuries: A New Target for Therapeutic Intervention

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recommendations! Published in 2022 at "Frontiers in Molecular Neuroscience"

DOI: 10.3389/fnmol.2022.816182

Abstract: Acute central nervous system (CNS) injuries, including ischemic stroke, traumatic brain injury (TBI), spinal cord injury (SCI) and subarachnoid hemorrhage (SAH), are the most common cause of death and disability around the world. As a… read more here.

Keywords: cns injuries; acute central; central nervous; acute cns ... See more keywords