Trehalose-Guanosine Glycopolymer Hydrogels Direct Adaptive Glia Responses in CNS Injury.
Sign Up to like & getrecommendations! Published in 2023 at "Advanced materials"
DOI: 10.1002/adma.202211774
Abstract: Neural tissue damaged after central nervous system (CNS) injury does not naturally regenerate but is instead replaced by non-neural fibrotic scar tissue that serves no neurological function. Scar-free repair to create a more permissive environment… read more here.
Keywords: trehalose guanosine; cns injury; ptreguo; injury ... See more keywords
Neurochemical signs of astrocytic and neuronal injury in acute COVID-19 normalizes during long-term follow-up
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DOI: 10.1016/j.ebiom.2021.103512
Abstract: Background Neurologic manifestations are well-recognized features of coronavirus disease 2019 (COVID-19). However, the longitudinal association of biomarkers reflecting CNS impact and neurological symptoms is not known. We sought to determine whether plasma biomarkers of CNS… read more here.
Keywords: acute phase; neurological symptoms; covid; cns injury ... See more keywords
Therapeutic use of extracellular mitochondria in CNS injury and disease
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DOI: 10.1016/j.expneurol.2019.113114
Abstract: In the central nervous system (CNS), neuronal functionality is highly dependent on mitochondrial integrity and activity. In the context of a damaged or diseased brain, mitochondrial dysfunction leads to reductions in ATP levels, thus impairing… read more here.
Keywords: use extracellular; therapeutic use; mitochondria cns; cns injury ... See more keywords
Role of NETosis in Central Nervous System Injury
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DOI: 10.1155/2022/3235524
Abstract: Central nervous system (CNS) injury is divided into brain injury and spinal cord injury and remains the most common cause of morbidity and mortality worldwide. Previous reviews have defined numerous inflammatory cells involved in this… read more here.
Keywords: cns injury; role netosis; injury; central nervous ... See more keywords
Mesenchymal stromal cells: cell-based therapies for traumatic central nervous system injuries.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of integrative neuroscience"
DOI: 10.31083/j.jin2102044
Abstract: Traumatic central nervous system (CNS) injury often causes irreversible impairment, and new alternative therapies for the treatment of CNS injury and sequelae are expected to be developed. Recently, mesenchymal stromal cells (MSCs) have started being… read more here.
Keywords: mesenchymal stromal; traumatic central; central nervous; cns injury ... See more keywords
The Role of Neurogenic Inflammation in Blood-Brain Barrier Disruption and Development of Cerebral Oedema Following Acute Central Nervous System (CNS) Injury
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DOI: 10.3390/ijms18081788
Abstract: Acute central nervous system (CNS) injury, encompassing traumatic brain injury (TBI) and stroke, accounts for a significant burden of morbidity and mortality worldwide, largely attributable to the development of cerebral oedema and elevated intracranial pressure… read more here.
Keywords: cerebral oedema; cns injury; brain; role ... See more keywords
Modulation of the Endocannabinoid System Following Central Nervous System Injury
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DOI: 10.3390/ijms20020388
Abstract: Central nervous system (CNS) injury, such as stroke or trauma, is known to increase susceptibility to various infections that adversely affect patient outcomes (CNS injury-induced immunodepression—CIDS). The endocannabinoid system (ECS) has been shown to have… read more here.
Keywords: system; nervous system; central nervous; endocannabinoid system ... See more keywords