The eyes have it: CNS leukemia presenting as optic neuritis
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Hematology"
DOI: 10.1007/s12185-020-03065-8
Abstract: A 35-year-old woman presented with acute left eye vision loss. 12 years earlier, she was treated for AML with induction chemotherapy and matched unrelated donor allogenic stem cell transplantation, complicated by persistent GVHD of lungs… read more here.
Keywords: leukemia presenting; eyes cns; optic nerve; cns leukemia ... See more keywords
Tgrx-678 Penetrates Blood-Brain Barrier and Exhibits Preclinical Anti-Tumor Activity in Murine Ph+ CNS Leukemia and ALL Models
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DOI: 10.1182/blood-2024-199958
Abstract: Central nervous system leukemia (CNSL) relapse is relatively common among Philadelphia chromosome-positive (Ph+) acute lymphoblastic leukemia (ALL) and chronic myeloid leukemia (CML) lymphoid blast crisis patients. TGRX-678, a novel allosteric inhibitor specifically targeting ABL1 myristoyl… read more here.
Keywords: brain; cns leukemia; tgrx 678; tumor ... See more keywords