Craniotomy versus biopsy for primary CNS lymphoma: An institutional series and nationwide NCDB‐PUF and SEER database study
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DOI: 10.1002/hon.2439_108
Abstract: (p < 0.0001) as the most important variables predicting better survival at diagnosis. However, in the multivariate analysis, only age ≤ 60 years (p < 0.005), male sex (p = 0.04) and ECOG read more here.
Keywords: cns lymphoma; craniotomy versus; lymphoma institutional; versus biopsy ... See more keywords
CSF interleukin 6 is a useful marker to distinguish pseudotumoral CNS inflammatory diseases from primary CNS lymphoma
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Neurology"
DOI: 10.1007/s00415-021-10453-5
Abstract: Interleukin 6 (IL-6) is a pleomorphic cytokine that can be found in the cerebrospinal fluid (CSF) in a wide spectrum of inflammatory pathologies of the central nervous system (CNS). Our aim was to characterize the… read more here.
Keywords: cns lymphoma; cns; inflammatory diseases; csf ... See more keywords
Diagnosis, treatment, and outcome of primary CNS lymphoma—a single-center experience
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DOI: 10.1007/s00701-022-05170-5
Abstract: Primary CNS lymphoma (PCNSL) is a highly aggressive non-Hodgkin lymphoma (NHL) that occurs in the CNS (e.g. brain, meninges, spinal cord, cerebrospinal fluid, or intraocular involvement) in the absence of systemic NHL. Tumor resection does… read more here.
Keywords: primary cns; lymphoma; cns lymphoma; single center ... See more keywords
Higher levels of progranulin in cerebrospinal fluid of patients with lymphoma and carcinoma with CNS metastasis
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DOI: 10.1007/s11060-017-2742-z
Abstract: Assessing central nervous system (CNS) involvement in patients with lymphoma or carcinoma is important in determining therapy and prognosis. Progranulin (PGRN) is a secreted glycosylated protein with roles in cancer growth and survival; it is… read more here.
Keywords: cns lymphoma; cns metastasis; cns; pgrn ... See more keywords
Clinical Features and Treatment Outcomes of Vitreoretinal Lymphoma according to Its Association with CNS Lymphoma
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DOI: 10.1080/09273948.2017.1421669
Abstract: ABSTRACT Purpose: To compare the clinical features and treatment outcomes of different types of vitreoretinal lymphoma (VRL) that presents primarily, secondarily, or concurrently in association with CNS lymphoma. Methods: We retrospectively reviewed the medical records… read more here.
Keywords: lymphoma; cns lymphoma; clinical features; cns ... See more keywords
Have treatment protocols for primary CNS lymphoma advanced in the past 10 years
Sign Up to like & getrecommendations! Published in 2019 at "Expert Review of Anticancer Therapy"
DOI: 10.1080/14737140.2019.1677157
Abstract: ABSTRACT Introduction: Primary CNS lymphomas (PCNSL) are highly aggressive tumors and optimal treatment is not yet defined. For the last two decades, clinical trials have focused on developing efficient chemotherapy protocols with or without dose-reduced… read more here.
Keywords: chemotherapy; cns lymphoma; treatment protocols; treatment ... See more keywords
NCMP-15. CNS LYMPHOMA: THE GREAT MIMICKER
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DOI: 10.1093/neuonc/noaa215.526
Abstract: Primary central nervous system lymphoma (PCNSL) is a variant of non-Hodgkin lymphoma, affecting the brain, leptomeninges, eyes, and spinal cord. PCNSL is a progressive disease with symptom onset occurring over weeks that presents with varied… read more here.
Keywords: cns lymphoma; diagnosis; patient year; year old ... See more keywords
RTHP-34. IMPROVED SURVIVAL IN CNS LYMPHOMA WITH SALVAGE LOW-DOSE WHOLE-BRAIN RADIOTHERAPY WITH FOCAL BOOST AND CONCURRENT TEMOZOLOMIDE
Sign Up to like & getrecommendations! Published in 2019 at "Neuro-Oncology"
DOI: 10.1093/neuonc/noz175.905
Abstract: There is no standard salvage radiotherapy (RT) regimen, nor a consensus on the concurrent chemotherapy use in CNS lymphoma. We assessed the efficacy of low-dose whole-brain radiotherapy (WBRT) with focal-boost to the area of disease… read more here.
Keywords: cns lymphoma; low dose; concurrent temozolomide; boost ... See more keywords
Temporalis muscle thickness predicts early relapse and short survival in primary CNS lymphoma.
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DOI: 10.1093/nop/npac087
Abstract: Background Most patients with primary CNS lymphoma (PCNSL) achieve durable remission whereas a minority die in the first year. Sarcopenia is a powerful predictor of mortality in the brain and systemic cancers. Temporalis muscle thickness… read more here.
Keywords: oncology; thin tmt; survival; short survival ... See more keywords
Safety and efficacy of induction immunochemotherapy with rituximab, methotrexate, ifosfamide, and vincristine (R‐MIV) in patients with primary CNS lymphoma including recent COVID‐19 pandemic experience
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DOI: 10.1111/bjh.18687
Abstract: Clinical data on primary central nervous system (CNS) lymphoma (PCNSL) patients is mostly generated from prospective studies, and many frail real‐world patients are not included. Recently,the diagnosis and treatment of PCNSL patients was confounded by… read more here.
Keywords: ifosfamide vincristine; rituximab methotrexate; covid pandemic; methotrexate ifosfamide ... See more keywords
Sustained Complete Remission in Multi-Relapsed Primary CNS Lymphoma Treated with Ibrutinib Monotherapy: A Case Report
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DOI: 10.1159/000518528
Abstract: Primary CNS lymphoma (PCNSL) is a highly aggressive malignant disease with a high recurrence rate and a poor prognosis. We present the case of a 71-year-old woman diagnosed with PCNSL in June 2010. After 3… read more here.
Keywords: complete remission; cns lymphoma; primary cns; case ... See more keywords