Downregulation of SF3B2 protects CNS neurons in models of multiple sclerosis
Sign Up to like & getrecommendations! Published in 2022 at "Annals of Clinical and Translational Neurology"
DOI: 10.1002/acn3.51717
Abstract: Neurodegeneration induced by inflammatory stress in multiple sclerosis (MS) leads to long‐term neurological disabilities that are not amenable to current immunomodulatory therapies. read more here.
Keywords: sclerosis; cns neurons; downregulation sf3b2; sf3b2 protects ... See more keywords
CNS Neurons Deposit Laminin α5 to Stabilize Synapses
Sign Up to like & getrecommendations! Published in 2017 at "Cell reports"
DOI: 10.1016/j.celrep.2017.10.028
Abstract: SUMMARY Synapses in the developing brain are structurally dynamic but become stable by early adulthood. We demonstrate here that an α5-subunit-containing laminin stabilizes synapses during this developmental transition. Hippocampal neurons deposit laminin α5 at synapses… read more here.
Keywords: neurons deposit; dendritic spine; stabilize synapses; laminin stabilize ... See more keywords
Serotonin induces or inhibits neuritic regeneration of leech CNS neurons depending on neuronal identity
Sign Up to like & getrecommendations! Published in 2019 at "Brazilian Journal of Medical and Biological Research"
DOI: 10.1590/1414-431x20187988
Abstract: Recovery of motor function after central nervous system (CNS) injury is dependent on the regeneration capacity of the nervous system, which is a multifactorial process influenced, among other things, by the role of neuromodulators such… read more here.
Keywords: induces inhibits; serotonin; serotonin induces; cns neurons ... See more keywords