Shed CNTNAP2 ectodomain is detectable in CSF and regulates Ca2+ homeostasis and network synchrony via PMCA2/ATP2B2
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DOI: 10.1016/j.neuron.2021.11.025
Abstract: Although many neuronal membrane proteins undergo proteolytic cleavage, little is known about the biological significance of neuronal ectodomain shedding (ES). Here, we show that the neuronal sheddome is detectable in human cerebrospinal fluid (hCSF) and… read more here.
Keywords: ectodomain; ca2 homeostasis; network synchrony; cntnap2 ecto ... See more keywords