Computational Exploration and Characterization of Potential Calcium Sensitizing Mutations in Cardiac Troponin C
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DOI: 10.1021/acs.jcim.2c01132
Abstract: Calcium-dependent heart muscle contraction is regulated by the cardiac troponin protein complex (cTn) and specifically by the N-terminal domain of its calcium binding subunit (cNTnC). cNTnC contains one calcium binding site (site II), and altered… read more here.
Keywords: calcium binding; calcium; cntnc; computational exploration ... See more keywords