A Novel “Inside‐Out” Intraocular Nanomedicine Delivery Mode for Nanomaterials’ Biological Effect Enhanced Choroidal Neovascularization Occlusion and Microenvironment Regulation
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Materials"
DOI: 10.1002/adma.202209690
Abstract: Photodynamic therapy (PDT) is commonly used in choroidal neovascularization (CNV) treatment due to the superior light transmittance of the eye. However, PDT often leads to surrounding tissue damage and further microenvironmental deterioration, including exacerbated hypoxia,… read more here.
Keywords: microenvironment; cnv; occlusion; choroidal neovascularization ... See more keywords
Silencing of YAP attenuates pericyte‐myofibroblast transition and subretinal fibrosis in experimental model of choroidal neovascularization
Sign Up to like & getrecommendations! Published in 2022 at "Cell Biology International"
DOI: 10.1002/cbin.11809
Abstract: Age‐related macular degeneration (AMD) is the main reason of irreversible vision loss in the elderly. The subretinal fibrosis subsequent to choroidal neovascularization (CNV) is an important feature in the late stage of wet AMD and… read more here.
Keywords: pericyte myofibroblast; subretinal fibrosis; cnv; choroidal neovascularization ... See more keywords
Identification of a dysregulated ceRNA network modulated by copy number variation‐driven lncRNAs in lung squamous cell carcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Environmental and Molecular Mutagenesis"
DOI: 10.1002/em.22509
Abstract: Lung cancer is primarily responsive for cancer death, and its progression is aggressively affected by copy number variation (CNV). Through bioinformatics approach, a ceRNA network of CNV‐driven lncRNAs in lung squamous cell carcinoma (LUSC) patients… read more here.
Keywords: cell; cerna network; cnv; lung ... See more keywords
Silencing fibroblast growth factor 7 inhibits krypton laser‐induced choroidal neovascularization in a rat model
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.28652
Abstract: Choroidal neovascularization (CNV), a characteristic of age‐related macular degeneration, is an underlying cause of severe vision loss among elderly patients. Fibroblast growth factor (FGF) is suggested to exert an important role in the pathogenesis of… read more here.
Keywords: growth factor; fgf7; cnv; choroidal neovascularization ... See more keywords
Estimate of genetic variants using CNV‐Seq for fetuses with oligohydramnios or polyhydramnios
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Genetics & Genomic Medicine"
DOI: 10.1002/mgg3.2089
Abstract: Oligohydramnios or polyhydramnios, is associated with chromosomal aberrations, particularly aneuploidy. However, its correlation with copy number variation (CNV) remains unclear. read more here.
Keywords: estimate genetic; using cnv; cnv; oligohydramnios polyhydramnios ... See more keywords
Morphological prognosis prediction of choroid neovascularization from longitudinal SD-OCT images.
Sign Up to like & getrecommendations! Published in 2023 at "Medical physics"
DOI: 10.1002/mp.16294
Abstract: BACKGROUND Choroid neovascularization (CNV) has no obvious symptoms in the early stage, but with its gradual expansion, leakage, rupture, and bleeding, it can cause vision loss and central scotoma. In some severe cases, it will… read more here.
Keywords: network; cnv; growth; growth prediction ... See more keywords
Evolution of multiple target-site resistance mechanisms in individual plants of glyphosate-resistant Eleusine indica from China.
Sign Up to like & getrecommendations! Published in 2021 at "Pest management science"
DOI: 10.1002/ps.6527
Abstract: BACKGROUND Glyphosate has been used for weed control in South China in various situations for four decades, and most Eleusine indica populations are suspected to have evolved resistance to glyphosate. This research investigated underling target-site… read more here.
Keywords: resistance; glyphosate; target site; cnv ... See more keywords
Topographic Correspondence of Macular Atrophy With Choroidal Neovascularization in Ranibizumab-treated Eyes of the TREX-AMD Trial.
Sign Up to like & getrecommendations! Published in 2018 at "American journal of ophthalmology"
DOI: 10.1016/j.ajo.2018.05.008
Abstract: PURPOSE To quantify the extent of topographic correspondence between baseline (BSL) choroidal neovascularization (CNV) and macular atrophy (MA) at follow-up in eyes with neovascular age-related macular degeneration (NVAMD). DESIGN Post hoc analysis of randomized controlled… read more here.
Keywords: trial; macular atrophy; cnv; topographic correspondence ... See more keywords
Simultaneous bilateral choroidal neovascularization associated with Staphylococcus aureus infective endocarditis: A case report
Sign Up to like & getrecommendations! Published in 2021 at "American Journal of Ophthalmology Case Reports"
DOI: 10.1016/j.ajoc.2021.101037
Abstract: Purpose To report a case of simultaneous bilateral choroidal neovascularization (CNV) associated with Staphylococcus aureus infective endocarditis. Observations A 35-year-old man presented with acute visual impairment 14 days after cardiac surgery for acute infective endocarditis… read more here.
Keywords: infective endocarditis; simultaneous bilateral; case; report ... See more keywords
An Organismal CNV Mutator Phenotype Restricted to Early Human Development
Sign Up to like & getrecommendations! Published in 2017 at "Cell"
DOI: 10.1016/j.cell.2017.01.037
Abstract: De novo copy number variants (dnCNVs) arising at multiple loci in a personal genome have usually been considered to reflect cancer somatic genomic instabilities. We describe a multiple dnCNV (MdnCNV) phenomenon in which individuals with genomic… read more here.
Keywords: phenotype restricted; organismal cnv; cnv mutator; mutator phenotype ... See more keywords
Repurposing bortezomib for choroidal neovascularization treatment via antagonizing VEGF-A and PDGF-D mediated signaling.
Sign Up to like & getrecommendations! Published in 2021 at "Experimental eye research"
DOI: 10.1016/j.exer.2021.108446
Abstract: Neovascular age-related macular degeneration (neoAMD) is the leading cause of blindness in AMD and manifests as choroidal neovascularization (CNV). Anti-vascular endothelial growth factor (VEGF) therapies are the mainstay treatments but with limited efficacy and cause… read more here.
Keywords: choroidal neovascularization; antagonizing vegf; injection; cnv ... See more keywords