A Novel “Inside‐Out” Intraocular Nanomedicine Delivery Mode for Nanomaterials’ Biological Effect Enhanced Choroidal Neovascularization Occlusion and Microenvironment Regulation
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Materials"
DOI: 10.1002/adma.202209690
Abstract: Photodynamic therapy (PDT) is commonly used in choroidal neovascularization (CNV) treatment due to the superior light transmittance of the eye. However, PDT often leads to surrounding tissue damage and further microenvironmental deterioration, including exacerbated hypoxia,… read more here.
Keywords: microenvironment; cnv; occlusion; choroidal neovascularization ... See more keywords
The Optimized Lipid‐Modified Prodrug for CNV Treatment
Sign Up to like & getrecommendations! Published in 2025 at "Advanced Materials"
DOI: 10.1002/adma.202419263
Abstract: Choroidal neovascularization (CNV) is a prevalent cause of vision impairment. The primary treatment for CNV involves intravitreal injections of anti‐vascular endothelial growth factor antibodies. Nevertheless, this approach still faces numerous limitations like poor patient compliance,… read more here.
Keywords: treatment; c20 nps; optimized lipid; c20 ... See more keywords
Silencing of YAP attenuates pericyte‐myofibroblast transition and subretinal fibrosis in experimental model of choroidal neovascularization
Sign Up to like & getrecommendations! Published in 2022 at "Cell Biology International"
DOI: 10.1002/cbin.11809
Abstract: Age‐related macular degeneration (AMD) is the main reason of irreversible vision loss in the elderly. The subretinal fibrosis subsequent to choroidal neovascularization (CNV) is an important feature in the late stage of wet AMD and… read more here.
Keywords: pericyte myofibroblast; subretinal fibrosis; cnv; choroidal neovascularization ... See more keywords
Identification of a dysregulated ceRNA network modulated by copy number variation‐driven lncRNAs in lung squamous cell carcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Environmental and Molecular Mutagenesis"
DOI: 10.1002/em.22509
Abstract: Lung cancer is primarily responsive for cancer death, and its progression is aggressively affected by copy number variation (CNV). Through bioinformatics approach, a ceRNA network of CNV‐driven lncRNAs in lung squamous cell carcinoma (LUSC) patients… read more here.
Keywords: cell; cerna network; cnv; lung ... See more keywords
Silencing fibroblast growth factor 7 inhibits krypton laser‐induced choroidal neovascularization in a rat model
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.28652
Abstract: Choroidal neovascularization (CNV), a characteristic of age‐related macular degeneration, is an underlying cause of severe vision loss among elderly patients. Fibroblast growth factor (FGF) is suggested to exert an important role in the pathogenesis of… read more here.
Keywords: growth factor; fgf7; cnv; choroidal neovascularization ... See more keywords
Estimate of genetic variants using CNV‐Seq for fetuses with oligohydramnios or polyhydramnios
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Genetics & Genomic Medicine"
DOI: 10.1002/mgg3.2089
Abstract: Oligohydramnios or polyhydramnios, is associated with chromosomal aberrations, particularly aneuploidy. However, its correlation with copy number variation (CNV) remains unclear. read more here.
Keywords: estimate genetic; using cnv; cnv; oligohydramnios polyhydramnios ... See more keywords
Morphological prognosis prediction of choroid neovascularization from longitudinal SD-OCT images.
Sign Up to like & getrecommendations! Published in 2023 at "Medical physics"
DOI: 10.1002/mp.16294
Abstract: BACKGROUND Choroid neovascularization (CNV) has no obvious symptoms in the early stage, but with its gradual expansion, leakage, rupture, and bleeding, it can cause vision loss and central scotoma. In some severe cases, it will… read more here.
Keywords: network; cnv; growth; growth prediction ... See more keywords
Prenatal Exome Sequencing Analysis in Fetuses With Structural Anomalies: A Multicenter Prospective Cohort Study With Practical Implications.
Sign Up to like & getrecommendations! Published in 2025 at "Prenatal diagnosis"
DOI: 10.1002/pd.70006
Abstract: OBJECTIVE To evaluate the diagnostic value of prenatal exome sequencing (ES) integrated with copy number variant (CNV) and single nucleotide variant (SNV) analysis (ES-CNV/SNV) in fetuses with structural anomalies following negative chromosomal microarray analysis (CMA)… read more here.
Keywords: analysis; structural anomalies; cnv snv; cnv ... See more keywords
Evolution of multiple target-site resistance mechanisms in individual plants of glyphosate-resistant Eleusine indica from China.
Sign Up to like & getrecommendations! Published in 2021 at "Pest management science"
DOI: 10.1002/ps.6527
Abstract: BACKGROUND Glyphosate has been used for weed control in South China in various situations for four decades, and most Eleusine indica populations are suspected to have evolved resistance to glyphosate. This research investigated underling target-site… read more here.
Keywords: resistance; glyphosate; target site; cnv ... See more keywords
Simultaneous GA and CNV/MNV: incidence, characteristics, and treatments
Sign Up to like & getrecommendations! Published in 2025 at "Graefe's Archive for Clinical and Experimental Ophthalmology"
DOI: 10.1007/s00417-024-06721-5
Abstract: Understanding the clinical characteristics and underlying mechanisms of simultaneous geographic atrophy (GA) and choroidal neovascularization (CNV)/macular neovascularization (MNV) is necessary for the long-term management of late age-related macular degeneration (AMD) in clinical practice. The authors… read more here.
Keywords: clinical characteristics; neovascularization; simultaneous cnv; cnv mnv ... See more keywords
Granzyme B degrades extracellular matrix and promotes inflammation and choroidal neovascularization
Sign Up to like & getrecommendations! Published in 2024 at "Angiogenesis"
DOI: 10.1007/s10456-024-09909-9
Abstract: Age-related macular degeneration (AMD) is a common retinal neurodegenerative disease among the elderly. Neovascular AMD (nAMD), a leading cause of AMD-related blindness, involves choroidal neovascularization (CNV), which can be suppressed by anti-angiogenic treatments. However, current… read more here.
Keywords: extracellular matrix; amd; cnv; inflammation ... See more keywords