Kir5.1‐dependent CO2/H+‐sensitive currents contribute to astrocyte heterogeneity across brain regions
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DOI: 10.1002/glia.23898
Abstract: Astrocyte heterogeneity is an emerging concept in which astrocytes within or between brain regions show variable morphological and/or gene expression profiles that presumably reflect different functional roles. Recent evidence indicates that retrotrapezoid nucleus (RTN) astrocytes… read more here.
Keywords: astrocyte heterogeneity; co2; brain regions; co2 sensitive ... See more keywords
Patch-to-Seq and Transcriptomic Analyses Yield Molecular Markers of Functionally Distinct Brainstem Serotonin Neurons
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DOI: 10.3389/fnsyn.2022.910820
Abstract: Acute regulation of CO2 and pH homeostasis requires sensory feedback from peripheral (carotid body) and central (central) CO2/pH sensitive cells – so called respiratory chemoreceptors. Subsets of brainstem serotonin (5-HT) neurons in the medullary raphe… read more here.
Keywords: brainstem serotonin; patch seq; functionally distinct; co2 sensitive ... See more keywords
CO2-Sensitive Connexin Hemichannels in Neurons and Glia: Three Different Modes of Signalling?
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DOI: 10.3390/ijms22147254
Abstract: Connexins can assemble into either gap junctions (between two cells) or hemichannels (from one cell to the extracellular space) and mediate cell-to-cell signalling. A subset of connexins (Cx26, Cx30, Cx32) are directly sensitive to CO2… read more here.
Keywords: modes signalling; neurons glia; sensitive connexin; connexin hemichannels ... See more keywords