Elevating 4-hydroxycoumarin production through alleviating thioesterase-mediated salicoyl-CoA degradation.
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DOI: 10.1016/j.ymben.2017.05.006
Abstract: Acyl-CoAs are essential intermediates in the biosynthetic pathways of a number of industrially and pharmaceutically important molecules. When these pathways are reconstituted in a heterologous microbial host for metabolic engineering purposes, the acyl-CoAs may be… read more here.
Keywords: production; coa; coa degradation; thioesterase ... See more keywords