Acetyl-CoA flux from the cytosol to the ER regulates engagement and quality of the secretory pathway
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DOI: 10.1038/s41598-021-81447-6
Abstract: Nε-lysine acetylation in the ER is an essential component of the quality control machinery. ER acetylation is ensured by a membrane transporter, AT-1/SLC33A1, which translocates cytosolic acetyl-CoA into the ER lumen, and two acetyltransferases, ATase1… read more here.
Keywords: coa flux; secretory pathway; quality; acetyl coa ... See more keywords