Phenolic metabolism in the hornwort Anthoceros agrestis: 4-coumarate CoA ligase and 4-hydroxybenzoate CoA ligase
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DOI: 10.1007/s00299-020-02552-w
Abstract: 4-Coumarate coenzyme A ligase and 4-hydroxybenzoate coenzyme A ligase from the hornwort Anthoceros agrestis expressed in E. coli were characterized on biochemical and molecular levels and showed interesting substrate specificities. Acyl-activating enzymes are associated with… read more here.
Keywords: coa ligase; anthoceros agrestis; coumaric acid; acid ... See more keywords
Overexpressing codon-adapted fusion proteins of 4-coumaroyl-CoA ligase (4CL) and stilbene synthase (STS) for resveratrol production in Chlamydomonas reinhardtii
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Applied Phycology"
DOI: 10.1007/s10811-020-02123-2
Abstract: Resveratrol is a plant phenolic secondary metabolite derived from phenylpropane metabolic pathway. It is a phytoalexin of high pharmaceutical interest produced in the defense response of plants. To produce resveratrol in Chlamydomonas reinhardtii, 4-coumaroyl-CoA ligase… read more here.
Keywords: coa ligase; resveratrol; ligase 4cl; coumaroyl coa ... See more keywords
Development of a Biosensor for Crotonobetaine-CoA-Ligase Screening based on Elucidation of the Escherichia coli Carnitine Metabolism.
Sign Up to like & getrecommendations! Published in 2020 at "ACS synthetic biology"
DOI: 10.1021/acssynbio.0c00234
Abstract: L-Carnitine is essential in the intermediary metabolism of eukaryotes and involved in β-oxidation of medium- and long-chain fatty acids, thus, it has applications for medicinal purposes and as dietary supplement. In addition, L-carnitine plays roles… read more here.
Keywords: coa ligase; carnitine metabolism; metabolism; biosensor ... See more keywords
Succinyl-CoA ligase ADP-forming subunit beta promotes stress granule assembly to regulate redox and drive cancer metastasis.
Sign Up to like & getrecommendations! Published in 2023 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2217332120
Abstract: Although recent studies demonstrate active mitochondrial metabolism in cancers, the precise mechanisms through which mitochondrial factors contribute to cancer metastasis remain elusive. Through a customized mitochondrion RNAi screen, we identified succinyl-CoA ligase ADP-forming subunit beta… read more here.
Keywords: metastasis; succinyl coa; cancer metastasis; coa ligase ... See more keywords