Overexpression of HMG-CoA synthase promotes Arabidopsis root growth and adversely affects glucosinolate biosynthesis
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Experimental Botany"
DOI: 10.1093/jxb/erz420
Abstract: Inhibition of 3-hydroxy-3-methylglutaryl-CoA synthase (HMGS) retarded root growth in Arabidopsis seedlings by reducing stigmasterol, auxin, and cytokinin levels. Differentially expressed proteins and metabolite changes revealed a relationship between HMGS and glucosinolate biosynthesis. read more here.
Keywords: coa synthase; glucosinolate biosynthesis; root growth;
Clinical, Biochemical, Molecular, and Outcome Features of Mitochondrial 3-Hydroxy-3-Methylglutaryl-CoA Synthase Deficiency in 10 Chinese Patients
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2021.816779
Abstract: Background: Mitochondrial 3-hydroxy-3-methylglutaryl-CoA synthase deficiency (HMGCS2D) is a rare autosomal recessive metabolic disorder caused by mutations of the HMGCS2 gene. To date, no more than 60 patients have been reported throughout the world. Purpose: To… read more here.
Keywords: synthase deficiency; methylglutaryl coa; mitochondrial hydroxy; chinese patients ... See more keywords