Articles with "coacervate" as a keyword



A Novel Coacervate Embolic Agent for Tumor Chemoembolization

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Published in 2024 at "Advanced Healthcare Materials"

DOI: 10.1002/adhm.202304488

Abstract: Transcatheter arterial chemoembolization (TACE) has proven effective in blocking tumor‐supplied arteries and delivering localized chemotherapeutic treatment to combat tumors. However, traditional embolic TACE agents exhibit certain limitations, including insufficient chemotherapeutic drug‐loading and sustained‐release capabilities, non‐biodegradability,… read more here.

Keywords: tumor chemoembolization; coacervate; embolic agent; agent ... See more keywords

Thermoresponsive Complex Coacervate-Based Underwater Adhesive.

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Published in 2019 at "Advanced materials"

DOI: 10.1002/adma.201808179

Abstract: Sandcastle worms have developed protein-based adhesives, which they use to construct protective tubes from sand grains and shell bits. A key element in the adhesive delivery is the formation of a fluidic complex coacervate phase.… read more here.

Keywords: underwater adhesive; based underwater; coacervate based; complex coacervate ... See more keywords

A Robust Salty Water Adhesive by Counterion Exchange Induced Coacervate.

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Published in 2019 at "Macromolecular rapid communications"

DOI: 10.1002/marc.201800758

Abstract: Counterion exchange of charged macromolecules has comprehensive implications in biological and synthetic systems such as protein function, biosignaling, ion conducting, and separation, but the correlation between the dynamic ion exchange, polyelectrolyte phase separation, and functionality… read more here.

Keywords: counterion exchange; salty water; coacervate; exchange ... See more keywords

Myocardial protection by heparin-based coacervate of FGF10

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Published in 2021 at "Bioactive Materials"

DOI: 10.1016/j.bioactmat.2020.12.002

Abstract: Heart disease is still the leading killer all around the world, and its incidence is expected to increase over the next decade. Previous reports have already shown the role of fibroblast growth factor10 (FGF10) in… read more here.

Keywords: fgf10; free fgf10; heparin; treatment ... See more keywords

Complex coacervates formed across liquid interfaces: A self-consistent field analysis.

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Published in 2017 at "Advances in colloid and interface science"

DOI: 10.1016/j.cis.2016.07.001

Abstract: The Scheutjens-Fleer self-consistent field (SF-SCF) theory is used to study complexation between two oppositely charged polyelectrolytes across an interface formed by two solvents, here called oil and water. The focus is on the composition and… read more here.

Keywords: self consistent; film; mesoscopically thin; consistent field ... See more keywords

Molecular and structural basis of low interfacial energy of complex coacervates in water.

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Published in 2017 at "Advances in colloid and interface science"

DOI: 10.1016/j.cis.2016.07.003

Abstract: Complex coacervate refers to a phase-separated fluid, typically of two oppositely charged polyelectrolytes in solution, representing a complex fluid system that has been shown to be of essential interest to biological systems, as well as… read more here.

Keywords: fluid; water; low interfacial; complex coacervate ... See more keywords

Scale-up synthesis of a polymer designed for protein therapy

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Published in 2019 at "European Polymer Journal"

DOI: 10.1016/j.eurpolymj.2019.05.032

Abstract: Abstract Here we report optimization and scale-up of a biodegradable polycation, poly(ethylene argininylaspartate diglyceride) (PEAD) for the purpose of clinical translation. This polycation complexes heparin to form a coacervate. The resultant complex coacervate acts as… read more here.

Keywords: scale synthesis; synthesis; coacervate; synthesis polymer ... See more keywords
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Gum Arabic/Lysozyme coacervate phase similar in structure to multilamellar liposomes

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Published in 2020 at "Food Hydrocolloids"

DOI: 10.1016/j.foodhyd.2020.105749

Abstract: Abstract It is known that the complex coacervation (CC) of biopolymers can induce conformational and structural changes of the interacting macromolecules. However, effect of such changes on the localization of biopolymers within the complex coacervate… read more here.

Keywords: coacervate phase; phase; gum arabic; structure ... See more keywords

Rheological and structural characteristics of whey protein-pectin complex coacervates

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Published in 2018 at "Journal of Food Engineering"

DOI: 10.1016/j.jfoodeng.2018.02.007

Abstract: Abstract Complex coacervation of protein/polysaccharide has found much interest for the encapsulation of bioactive materials. The rheological properties of the coacervates of whey protein/high methoxyl pectin (WPI/HMP) at different pH including 3.0, 3.5 and 4.0… read more here.

Keywords: characteristics whey; structural characteristics; rheological structural; pectin ... See more keywords

Membranized Coacervate Microdroplets: from Versatile Protocell Models to Cytomimetic Materials

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Published in 2023 at "Accounts of Chemical Research"

DOI: 10.1021/acs.accounts.2c00696

Abstract: Conspectus Although complex coacervate microdroplets derived from associative phase separation of counter-charged electrolytes have emerged as a broad platform for the bottom-up construction of membraneless, molecularly crowded protocells, the absence of an enclosing membrane limits… read more here.

Keywords: coacervate; membranized coacervate; cytomimetic materials; membrane ... See more keywords

Polysaccharide-Based Coacervate Microgel Bearing Cationic Peptides That Achieve Dynamic Cell-Membrane Structure Alteration and Facile Cytosolic Infusion of IgGs.

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Published in 2024 at "Bioconjugate chemistry"

DOI: 10.1021/acs.bioconjchem.4c00344

Abstract: Conjugates of the biocompatible polysaccharide pullulan with a cell membrane permeabilizing peptide L17E (PL-L17Es) were prepared with the aim of producing complex coacervates with pronounced intracellular antibody (IgG) delivery activity and stable structures. Coacervates with… read more here.

Keywords: igg; infusion; coacervate; cell membrane ... See more keywords