Articles with "coacervate droplets" as a keyword



Selective separation of dyes and tetracycline hydrochloride in polymer‐nucleotide coacervate droplets

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Published in 2024 at "Journal of Applied Polymer Science"

DOI: 10.1002/app.56430

Abstract: This paper reports the formation of coacervates by the electrostatic interaction of poly (diallyldimethylammonium chloride) (PDDA) and adenosine triphosphate (ATP) in aqueous solution, examining its formation conditions, stability, and efficiency in separation. The ideal concentration… read more here.

Keywords: separation; tetracycline hydrochloride; separation dyes; coacervate droplets ... See more keywords

Selective Accumulation to Tumor Cells with Coacervate Droplets Formed from a Water-Insoluble Acrylate Polymer.

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Published in 2022 at "Biomacromolecules"

DOI: 10.1021/acs.biomac.1c01343

Abstract: Selective targeting of specific cells without the use of biological ligands has not been achieved. In the present study, we revealed that the coacervate droplets formed from poly(2-methoxyethyl acrylate) (PMEA) and its derivatives selectively accumulated… read more here.

Keywords: pmea derivatives; water; tumor cells; droplets formed ... See more keywords

Thermophilic Behavior of Heat-Dissociative Coacervate Droplets.

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Published in 2024 at "Nano letters"

DOI: 10.1021/acs.nanolett.4c03058

Abstract: In exploring the genesis of life, liquid-liquid phase-separated coacervate droplets have been proposed as primitive protocells. Within the hydrothermal hypothesis, these droplets would emerge from molecule-rich hot fluids and thus be subjected to temperature gradients.… read more here.

Keywords: dissociative coacervate; behavior heat; heat; thermophilic behavior ... See more keywords

Encoding Coacervate Droplets with Paramagnetism for Dynamical Reconfigurability and Spatial Addressability.

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Published in 2023 at "ACS nano"

DOI: 10.1021/acsnano.2c09617

Abstract: It is an ongoing endeavor in chemistry and materials science to regulate coacervate droplets on a physiologically relevant spatiotemporal scale to ultimately match or even surpass living cells' precision, complexity, and functionality. Herein, we develop… read more here.

Keywords: encoding coacervate; dynamical reconfigurability; droplets paramagnetism; paramagnetism dynamical ... See more keywords
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Active coacervate droplets are protocells that grow and resist Ostwald ripening

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Published in 2021 at "Nature Communications"

DOI: 10.1038/s41467-021-24111-x

Abstract: Active coacervate droplets are liquid condensates coupled to a chemical reaction that turns over their components, keeping the droplets out of equilibrium. This turnover can be used to drive active processes such as growth, and… read more here.

Keywords: active coacervate; ostwald ripening; droplets protocells; coacervate droplets ... See more keywords

DNA dynamics in complex coacervate droplets and micelles

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Published in 2022 at "Soft Matter"

DOI: 10.1039/d1sm01787j

Abstract: Single stranded DNA (ssDNA), or another polyanion, can be mixed with polycations to form liquid-like complex coacervates. When the polycations are replaced by cationic–neutral diblock copolymers, complex coacervate core micelles (C3Ms) can be formed instead.… read more here.

Keywords: dna; coacervate droplets; length; droplets micelles ... See more keywords

Assembly of biomimetic microreactors using caged-coacervate droplets.

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Published in 2023 at "Nanoscale"

DOI: 10.1039/d2nr05101j

Abstract: Complex coacervates are liquid-like droplets that can be used to create adaptive cell-like compartments. These compartments offer a versatile platform for the construction of bioreactors inspired by living cells. However, the lack of a membrane… read more here.

Keywords: microreactors using; caged coacervate; assembly biomimetic; using caged ... See more keywords

Manipulation of coacervate droplets with an electric field

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Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"

DOI: 10.1073/pnas.2203483119

Abstract: Significance Many of the unique properties of biological materials are derived from the highly charged nature of the constituent molecules and their diffuse counterion clouds, which often render such materials intrinsically polarizable, and thus highly… read more here.

Keywords: electric field; manipulation coacervate; coacervate droplets; field ... See more keywords

Did the exposure of coacervate droplets to rain make them the first stable protocells?

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Published in 2024 at "Science Advances"

DOI: 10.1126/sciadv.adn9657

Abstract: Membraneless coacervate microdroplets have long been proposed as model protocells as they can grow, divide, and concentrate RNA by natural partitioning. However, the rapid exchange of RNA between these compartments, along with their rapid fusion,… read more here.

Keywords: rain make; first stable; exposure coacervate; droplets rain ... See more keywords