BVES‐AS1 inhibits the malignant behaviors of colon adenocarcinoma cells via regulating BVES
Sign Up to like & getrecommendations! Published in 2021 at "Cell Biology International"
DOI: 10.1002/cbin.11634
Abstract: The underexpression of the long noncoding RNA blood vessel epicardial substance antisense RNA 1 (BVES‐AS1) has been shown in colon adenocarcinoma (COAD) patients. However, its role in COAD remains to be explored. This study aimed… read more here.
Keywords: colon adenocarcinoma; inhibits malignant; bves as1; as1 inhibits ... See more keywords
miR-1307-3p overexpression inhibits cell proliferation and promotes cell apoptosis by targeting ISM1 in colon cancer.
Sign Up to like & getrecommendations! Published in 2019 at "Molecular and cellular probes"
DOI: 10.1016/j.mcp.2019.101445
Abstract: BACKGROUND colon adenocarcinoma (COAD) is the most common malignant tumor of gastrointestinal tract. Our study attempts to explore the effect of miR-1307-3p on biological function of COAD cells and its connection with isthmin 1 (ISM1).… read more here.
Keywords: mir 1307; mir; colon; proliferation ... See more keywords
Construction and verification of a histone deacetylases-related prognostic signature model for colon cancer
Sign Up to like & getrecommendations! Published in 2024 at "Scientific Reports"
DOI: 10.1038/s41598-024-59724-x
Abstract: Histone deacetylases (HDACs) contribute significantly to the initiation, progression, and prognosis of colorectal adenocarcinoma (COAD). Additionally, HDACs regulate the tumor microenvironment, immune escape, and tumor stem cells, and are closely linked to COAD prognosis. We… read more here.
Keywords: risk; coad; risk scores; histone deacetylases ... See more keywords
Focusing on DC cells to optimize the prediction of prognosis and innovative treatment strategies for colon cancer
Sign Up to like & getrecommendations! Published in 2025 at "Scientific Reports"
DOI: 10.1038/s41598-025-01792-8
Abstract: Colon adenocarcinoma (COAD) is a leading cause of cancer-related mortality worldwide, with immune cells, particularly dendritic cells (DCs), playing an essential part in the advancement of tumors and immunotherapy response. However, the prognostic significance of… read more here.
Keywords: treatment strategies; cancer; dcri; coad ... See more keywords
Identification of ferroptosis related genes and subtypes in colorectal cancer
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DOI: 10.1038/s41598-025-08901-7
Abstract: Colorectal cancer (CRC) is the third most common cancer and the second leading cause of cancer-related deaths worldwide. Increasing evidence has shown that ferroptosis plays a significant regulatory role in the occurrence and progression of… read more here.
Keywords: colorectal cancer; ferroptosis related; cancer; related genes ... See more keywords
Metformin modulates FJX1 via upregulation of Hsa-miR-1306-3p to suppress colon adenocarcinoma viability
Sign Up to like & getrecommendations! Published in 2025 at "Scientific Reports"
DOI: 10.1038/s41598-025-91022-y
Abstract: Metformin, widely used for the treatment of type 2 diabetes, has recently gained attention for its potential anticancer properties. Several studies have shown that metformin treatment inhibits cell viability in colon adenocarcinoma (COAD); however, the… read more here.
Keywords: mir 1306; treatment; coad; hsa mir ... See more keywords
Mining novel cell glycolysis related gene markers that can predict the survival of colon adenocarcinoma patients
Sign Up to like & getrecommendations! Published in 2020 at "Bioscience Reports"
DOI: 10.1042/bsr20201427
Abstract: Abstract Colon adenocarcinoma (COAD) is a malignant gastrointestinal tumor, often occurring in the left colon, which is regulated by glycolysis-related processes. In past studies, multiple genes that influence the prognosis for survival have been discovered… read more here.
Keywords: prognosis; coad; gene; glycolysis ... See more keywords
LncRNA ubiquitin-binding protein domain protein 10 antisense RNA 1 inhibits colon adenocarcinoma progression via the miR-515-5p/slit guidance ligand 3 axis
Sign Up to like & getrecommendations! Published in 2022 at "Bioengineered"
DOI: 10.1080/21655979.2021.2024396
Abstract: ABSTRACT Dysregulated long non-coding RNAs (lncRNAs) play an important role in cancer progression. However, there have been limited reports to date of the involvement of ubiquitin-binding protein domain protein 10 antisense RNA 1 (UBXN10-AS1) in… read more here.
Keywords: binding protein; ubiquitin binding; coad; ubxn10 as1 ... See more keywords
FOXM1/NCAPH activates glycolysis to promote colon adenocarcinoma stemness and 5-FU resistance.
Sign Up to like & getrecommendations! Published in 2023 at "Anti-cancer drugs"
DOI: 10.1097/cad.0000000000001526
Abstract: Chemotherapy using 5-fluorouracil (5-FU) is currently considered the most effective treatment for advanced colon adenocarcinoma (COAD). However, drug resistance remains a major obstacle in treating COAD. Non-SMC condensin I complex subunit H (NCAPH) is known… read more here.
Keywords: resistance; foxm1 ncaph; coad; stemness resistance ... See more keywords
MiRNA-based model for predicting the TMB level in colon adenocarcinoma based on a LASSO logistic regression method
Sign Up to like & getrecommendations! Published in 2021 at "Medicine"
DOI: 10.1097/md.0000000000026068
Abstract: Abstract Some patients with advanced colon adenocarcinoma (COAD) are not sensitive to radiotherapy and chemotherapy, and as such, immunotherapy has become the most popular option for these patients. However, different patients respond differently to immunotherapy.… read more here.
Keywords: mirna based; coad; model; based model ... See more keywords
Bioinformatics analysis revealing clinical significance of MGAT5 in colon adenocarcinoma
Sign Up to like & getrecommendations! Published in 2025 at "Medicine"
DOI: 10.1097/md.0000000000045578
Abstract: This study investigates the expression and clinical significance of N-acetylglucosaminyltransferase V (MGAT5) in colon adenocarcinoma (COAD) using bioinformatics methods. The mRNA and protein expression of MGAT5 in COAD tissues and the expression of MGAT5 in… read more here.
Keywords: mgat5 colon; clinical significance; coad; expression ... See more keywords