BVES‐AS1 inhibits the malignant behaviors of colon adenocarcinoma cells via regulating BVES
Sign Up to like & getrecommendations! Published in 2021 at "Cell Biology International"
DOI: 10.1002/cbin.11634
Abstract: The underexpression of the long noncoding RNA blood vessel epicardial substance antisense RNA 1 (BVES‐AS1) has been shown in colon adenocarcinoma (COAD) patients. However, its role in COAD remains to be explored. This study aimed… read more here.
Keywords: colon adenocarcinoma; inhibits malignant; bves as1; as1 inhibits ... See more keywords
miR-1307-3p overexpression inhibits cell proliferation and promotes cell apoptosis by targeting ISM1 in colon cancer.
Sign Up to like & getrecommendations! Published in 2019 at "Molecular and cellular probes"
DOI: 10.1016/j.mcp.2019.101445
Abstract: BACKGROUND colon adenocarcinoma (COAD) is the most common malignant tumor of gastrointestinal tract. Our study attempts to explore the effect of miR-1307-3p on biological function of COAD cells and its connection with isthmin 1 (ISM1).… read more here.
Keywords: mir 1307; mir; colon; proliferation ... See more keywords
Mining novel cell glycolysis related gene markers that can predict the survival of colon adenocarcinoma patients
Sign Up to like & getrecommendations! Published in 2020 at "Bioscience Reports"
DOI: 10.1042/bsr20201427
Abstract: Abstract Colon adenocarcinoma (COAD) is a malignant gastrointestinal tumor, often occurring in the left colon, which is regulated by glycolysis-related processes. In past studies, multiple genes that influence the prognosis for survival have been discovered… read more here.
Keywords: prognosis; coad; gene; glycolysis ... See more keywords
LncRNA ubiquitin-binding protein domain protein 10 antisense RNA 1 inhibits colon adenocarcinoma progression via the miR-515-5p/slit guidance ligand 3 axis
Sign Up to like & getrecommendations! Published in 2022 at "Bioengineered"
DOI: 10.1080/21655979.2021.2024396
Abstract: ABSTRACT Dysregulated long non-coding RNAs (lncRNAs) play an important role in cancer progression. However, there have been limited reports to date of the involvement of ubiquitin-binding protein domain protein 10 antisense RNA 1 (UBXN10-AS1) in… read more here.
Keywords: binding protein; ubiquitin binding; coad; ubxn10 as1 ... See more keywords
FOXM1/NCAPH activates glycolysis to promote colon adenocarcinoma stemness and 5-FU resistance.
Sign Up to like & getrecommendations! Published in 2023 at "Anti-cancer drugs"
DOI: 10.1097/cad.0000000000001526
Abstract: Chemotherapy using 5-fluorouracil (5-FU) is currently considered the most effective treatment for advanced colon adenocarcinoma (COAD). However, drug resistance remains a major obstacle in treating COAD. Non-SMC condensin I complex subunit H (NCAPH) is known… read more here.
Keywords: resistance; foxm1 ncaph; coad; stemness resistance ... See more keywords
MiRNA-based model for predicting the TMB level in colon adenocarcinoma based on a LASSO logistic regression method
Sign Up to like & getrecommendations! Published in 2021 at "Medicine"
DOI: 10.1097/md.0000000000026068
Abstract: Abstract Some patients with advanced colon adenocarcinoma (COAD) are not sensitive to radiotherapy and chemotherapy, and as such, immunotherapy has become the most popular option for these patients. However, different patients respond differently to immunotherapy.… read more here.
Keywords: mirna based; coad; model; based model ... See more keywords
Low adenylate kinase 5 expression is predictive of poor prognosis and promotes tumour growth by regulating the cell‐cycle pathway
Sign Up to like & getrecommendations! Published in 2022 at "Clinical and Experimental Pharmacology and Physiology"
DOI: 10.1111/1440-1681.13680
Abstract: Colon adenocarcinoma (COAD) is one of the most common malignant tumours of the digestive system. Specific molecular markers play an important role in COAD diagnosis and therapy. Adenylate kinase 5 (AK5) is an enzyme that… read more here.
Keywords: ak5 expression; regulating cell; coad; cell cycle ... See more keywords
Circadian Clock Genes Are Correlated with Prognosis and Immune Cell Infiltration in Colon Adenocarcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Computational and Mathematical Methods in Medicine"
DOI: 10.1155/2022/1709918
Abstract: Background Colon adenocarcinoma (COAD) is a malignancy with a high incidence and is associated with poor quality of life. Dysfunction of circadian clock genes and disruption of normal rhythms are associated with the occurrence and… read more here.
Keywords: infiltration; circadian clock; immune cell; coad ... See more keywords
Ferroptosis-Related Long Noncoding RNAs as Prognostic Marker for Colon Adenocarcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Applied Bionics and Biomechanics"
DOI: 10.1155/2022/5220368
Abstract: Background The incidence of colon adenocarcinoma (COAD) has been increasing over time. Although ferroptosis and long noncoding RNAs (lncRNAs) have been extensively reported to participate in the tumorigenesis and development of COAD, few studies have… read more here.
Keywords: coad; risk; long noncoding; ferroptosis related ... See more keywords
MicroRNA-323a-3p Negatively Regulates NEK6 in Colon Adenocarcinoma Cells
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Oncology"
DOI: 10.1155/2022/7007718
Abstract: Objective The activity of NEK6 is enhanced in several cancer cells, including colon adenocarcinoma (COAD) cells. However, there are few reports on the microRNA (miRNA/miR) regulation of NEK6. In this study, we aimed to investigate… read more here.
Keywords: colon adenocarcinoma; nek6 mir; mir 323a; coad cells ... See more keywords
Comprehensive Analysis of Colorectal Cancer Immunity and Identification of Immune-Related Prognostic Targets
Sign Up to like & getrecommendations! Published in 2022 at "Disease Markers"
DOI: 10.1155/2022/7932655
Abstract: Colorectal cancer (COAD) is ranked as the third most common cancer and second in terms of cancer-related deaths worldwide. Due to its poor overall survival and prognosis, the incidents of COAD are significantly increasing. Although… read more here.
Keywords: coad; analysis; colorectal cancer; immune targets ... See more keywords