Analysis of Interleukin-1 Signaling Alterations of Colon Adenocarcinoma Identified Implications for Immunotherapy
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DOI: 10.3389/fimmu.2021.665002
Abstract: Immune checkpoint inhibitors (ICIs) have made breakthrough progress in the treatment of various malignant tumors. However, only some patients receiving ICIs obtain long-lasting clinical effects, and some patients still do not achieve remission. Improving the… read more here.
Keywords: receiving icis; analysis; group; patients receiving ... See more keywords
Lactate Metabolism-Associated lncRNA Pairs: A Prognostic Signature to Reveal the Immunological Landscape and Mediate Therapeutic Response in Patients With Colon Adenocarcinoma
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DOI: 10.3389/fimmu.2022.881359
Abstract: Background Lactate metabolism is critically involved in the tumor microenvironment (TME), as well as cancer progression. It is important to note, however, that lactate metabolism-related long non-coding RNAs (laRlncRNAs) remain incredibly understudied in colon adenocarcinoma… read more here.
Keywords: lactate metabolism; signature; colon adenocarcinoma; landscape ... See more keywords
Autophagy-related IFNG is a prognostic and immunochemotherapeutic biomarker of COAD patients
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DOI: 10.3389/fimmu.2023.1064704
Abstract: Background Numerous studies have shown autophagy affects cellular immune responses. This study aims to explore prognosis and immunotherapeutic biomarkers related to autophagy in colon adenocarcinoma (COAD). Methods Based on R software, we performed the ssGSEA,… read more here.
Keywords: ifng; group; analysis; autophagy related ... See more keywords
Therapeutic targets and functions of curcumol against COVID-19 and colon adenocarcinoma
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DOI: 10.3389/fnut.2022.961697
Abstract: Since 2019, the coronavirus disease (COVID-19) has caused 6,319,395 deaths worldwide. Although the COVID-19 vaccine is currently available, the latest variant of the virus, Omicron, spreads more easily than earlier strains, and its mortality rate… read more here.
Keywords: pharmacology; colon adenocarcinoma; covid coad; coad patients ... See more keywords
Puerarin: A Potential Therapeutic for Colon Adenocarcinoma (COAD) Patients Suffering From SARS-CoV-2 Infection
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DOI: 10.3389/fphar.2022.921517
Abstract: Patients with colonic adenocarcinoma (COAD) are at relatively high risk of SARS-CoV-2 infection. However, there is a lack of medical strategies to treat COVID-19/COAD comorbidity. Puerarin, a natural product, is a known antiviral, antitumor, and… read more here.
Keywords: target genes; signaling pathway; coad; covid coad ... See more keywords