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   Articles with "coadministration" as a keyword



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Drug‐Drug Interaction of Letermovir and Atorvastatin in Healthy Participants

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recommendations! Published in 2022 at "Clinical Pharmacology in Drug Development"

DOI: 10.1002/cpdd.1071

Abstract: Letermovir (MK‐8228/AIC246) is a cytomegalovirus (CMV) DNA terminase complex inhibitor for CMV prophylaxis in adult patients undergoing hematopoietic stem cell transplant. It is cytochrome P450 (CYP) 3A inhibitor and inhibits organic anion transporting polypeptide 1B1/3… read more here.

Keywords: atv cmax; coadministration; drug drug; letermovir ... See more keywords
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Evaluation of the Pharmacokinetic Drug Interaction of Capmatinib With Itraconazole and Rifampicin and Potential Impact on Renal Transporters in Healthy Subjects

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recommendations! Published in 2022 at "Journal of Clinical Pharmacology"

DOI: 10.1002/jcph.2153

Abstract: Capmatinib is a highly specific, potent, and selective mesenchymal–epithelial transition factor inhibitor predominantly eliminated by cytochrome P450 (CYP) 3A4 and aldehyde oxidase. Here, we investigated the effects of a strong CYP3A inhibitor (itraconazole) and a… read more here.

Keywords: day; inhibition; coadministration; concentration ... See more keywords
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Coadministration of Oligomeric Hyaluronic Acid-Modified Liposomes with Tumor-Penetrating Peptide-iRGD Enhances the Antitumor Efficacy of Doxorubicin against Melanoma.

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recommendations! Published in 2017 at "ACS applied materials & interfaces"

DOI: 10.1021/acsami.6b13738

Abstract: A safe and efficient tumor-targeting strategy based on oligomeric hyaluronic acid (HA) modification and coadministration of tumor-penetrating peptide-iRGD was successfully developed. In this study, common liposomes (cLip) were modified by oligomeric HA to obtain HA-Lip.… read more here.

Keywords: coadministration; tumor; irgd; dox ... See more keywords
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Safety of routine childhood vaccine coadministration versus separate vaccination

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recommendations! Published in 2022 at "BMJ Global Health"

DOI: 10.1136/bmjgh-2021-008215

Abstract: Introduction As new vaccines are developed more vaccine coadministrations vaccines are being offered to make delivery more practical for health systems and patients. We compared the safety of coadministered vaccines with separate vaccination for 20… read more here.

Keywords: coadministration; rir following; separate vaccination; fever rir ... See more keywords

Antidepressant-Like Effects and Cognitive Enhancement of Coadministration of Chaihu Shugan San and Fluoxetine: Dependent on the BDNF-ERK-CREB Signaling Pathway in the Hippocampus and Frontal Cortex

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recommendations! Published in 2020 at "BioMed Research International"

DOI: 10.1155/2020/2794263

Abstract: Background Fluoxetine (FLU) is the first-line and widely used medication for depression; however, FLU treatment is almost ineffective in 30%-40% of patients with depression. In addition, there are some problems in FLU treatment, such as… read more here.

Keywords: coadministration; erk; creb; css flu ... See more keywords
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Safety of integrated preventive chemotherapy for neglected tropical diseases

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recommendations! Published in 2022 at "PLoS Neglected Tropical Diseases"

DOI: 10.1371/journal.pntd.0010700

Abstract: Background Preventive chemotherapy (PC) is a central strategy for control and elimination of neglected tropical diseases (NTDs). Increased emphasis has been given to “integration” of NTD programs within health systems and coadministration of NTD drugs… read more here.

Keywords: safety; tropical diseases; coadministration; neglected tropical ... See more keywords
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Sitagliptin–Moringa oleifera coadministration did not delay the progression nor ameliorated functional and morphological anomalies in alloxan-induced diabetic nephropathy

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recommendations! Published in 2017 at "Indian Journal of Pharmacology"

DOI: 10.4103/ijp.ijp_832_16

Abstract: OBJECTIVE: Sitagliptin (ST) and Moringa oleifera (MO) Lam (Moringaceae) are used concomitantly by diabetic patients, with no study ascertaining for potential favorable or otherwise renal implications. We investigated the effect of coadministration of ST and… read more here.

Keywords: coadministration; moringa oleifera; induced diabetic; sitagliptin moringa ... See more keywords