Unveiling the phenylalanine coaggregation mechanism for a deep understanding of phenylketonuria disease
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DOI: 10.1038/s41598-025-19843-5
Abstract: The abnormal accumulation of phenylalanine is a defining feature of phenylketonuria (PKU) and is Linked to the formation of toxic, amyloid-like fibrils. To investigate the molecular mechanisms underlying this aggregation, we performed all-atom molecular dynamics… read more here.
Keywords: coaggregation; coaggregation mechanism; mechanism deep; phenylalanine coaggregation ... See more keywords