Implant stability in patients treated with platelet‐rich fibrin and bovine bone substitute for alveolar ridge preservation is associated with peripheral blood cells and coagulation factors
Sign Up to like & getrecommendations! Published in 2020 at "Clinical and Experimental Dental Research"
DOI: 10.1002/cre2.263
Abstract: The aim of the present study was to assess the association between dental implant stability and peripheral blood cell composition and levels of coagulation factors in patients treated with alveolar ridge preservation with platelet‐rich fibrin… read more here.
Keywords: alveolar ridge; implant stability; patients treated; ridge preservation ... See more keywords
Designing Smaller, Synthetic, Functional Mimetics of Sulfated Glycosaminoglycans as Allosteric Modulators of Coagulation Factors.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.3c00132
Abstract: Natural glycosaminoglycans (GAGs) are arguably the most diverse collection of natural products. Unfortunately, this bounty of structures remains untapped. Decades of research has realized only one GAG-like synthetic, small-molecule drug, fondaparinux. This represents an abysmal… read more here.
Keywords: modulators coagulation; coagulation factors; synthetic functional; smaller synthetic ... See more keywords
Unfavorably Altered Fibrin Clot Phenotype in Women Following Postpartum Hemorrhage of Unknown Cause: Effect of Lower Coagulation Factors
Sign Up to like & getrecommendations! Published in 2024 at "Thrombosis and Haemostasis"
DOI: 10.1055/a-2413-2966
Abstract: Background Increased clot permeability and susceptibility to lysis have been reported in women with heavy menstrual bleeding. We hypothesized that similar alterations in fibrin clot properties may also be present in women with postpartum hemorrhage… read more here.
Keywords: coagulation factors; unknown cause; clot; fibrin clot ... See more keywords
Knockdown of tmem183a in Zebrafish Causes Thrombocytopenia and Reduces Coagulation Factors, Disrupting Hemostasis
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DOI: 10.1055/a-2713-0711
Abstract: Background Transmembrane proteins are a class of membrane-embedded proteins with largely unexplored functions. Previous RNAseq analysis identified transmembrane protein 183a (tmem183a) expression in zebrafish thrombocytes, and its knockdown led to increased gill bleeding. This study… read more here.
Keywords: coagulation factors; tmem183a zebrafish; coagulation; hemostasis ... See more keywords
Uncovering Membrane-Bound Models of Coagulation Factors by Combined Experimental and Computational Approaches
Sign Up to like & getrecommendations! Published in 2021 at "Thrombosis and Haemostasis"
DOI: 10.1055/s-0040-1722187
Abstract: In the life sciences, including hemostasis and thrombosis, methods of structural biology have become indispensable tools for shedding light on underlying mechanisms that govern complex biological processes. Advancements of the relatively young field of computational… read more here.
Keywords: coagulation factors; biology; experimental computational; membrane bound ... See more keywords
Production of recombinant coagulation factors: Are humans the best host cells?
Sign Up to like & getrecommendations! Published in 2017 at "Bioengineered"
DOI: 10.1080/21655979.2017.1279767
Abstract: ABSTRACT The main treatment option for Hemophilia A/B patients involves the administration of recombinant coagulation factors on-demand or in a prophylactic approach. Despite the safety and efficacy of this replacement therapy, the development of antibodies… read more here.
Keywords: recombinant coagulation; coagulation factors; production recombinant; human cell ... See more keywords
The effects of coagulation factors on the risk of autoimmune diseases: A Mendelian randomization study
Sign Up to like & getrecommendations! Published in 2024 at "Medicine"
DOI: 10.1097/md.0000000000040893
Abstract: The objective of this study was to investigate the potential causal relationship between coagulation factors and autoimmune diseases (ADs). We employed Mendelian randomization to investigate the associations between selected 7 coagulation factors and 10 ADs,… read more here.
Keywords: risk; coagulation; mendelian randomization; autoimmune diseases ... See more keywords
Coagulation factors, anticoagulant proteins, and plasminogen in Mexican older adults
Sign Up to like & getrecommendations! Published in 2017 at "International Journal of Laboratory Hematology"
DOI: 10.1111/ijlh.12623
Abstract: Hemostasis protects upon the occurrence of vascular endothelial damage, with involving of different factors. The interaction of these factors in older adults is poorly known, and has been associated with different disorders. Therefore, we determined… read more here.
Keywords: factors anticoagulant; anticoagulant proteins; proteins plasminogen; coagulation factors ... See more keywords
Associations of coagulation factors IX and XI levels with incident coronary heart disease and ischemic stroke: the REGARDS study
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Thrombosis and Haemostasis"
DOI: 10.1111/jth.13698
Abstract: Essentials Coagulation factors (F) IX and XI have been implicated in cardiovascular disease (CVD) risk. We studied associations of FIX and FXI with incident coronary heart disease (CHD) and stroke. Higher FIX antigen was associated… read more here.
Keywords: heart disease; disease; coronary heart; coagulation factors ... See more keywords
Glucose metabolism affects coagulation factors: The NEO study
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Thrombosis and Haemostasis"
DOI: 10.1111/jth.14573
Abstract: It is insufficiently understood if there is an association between diabetes and VT, and what the underlying mechanism would be. read more here.
Keywords: factors neo; affects coagulation; metabolism affects; glucose metabolism ... See more keywords
Dengue virus NS1 leads to downregulation of HNF4 alpha in liver cells resulting in a decrease in coagulation factors I, V, X, and XIII, contributing to coagulopathy
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Virology"
DOI: 10.1128/jvi.01418-24
Abstract: ABSTRACT Dengue virus NS1 protein is a major pathogenic protein. In this study, we examined the role of NS1 in coagulopathy associated with Dengue infection, a common feature of Dengue virus pathogenesis. Since most coagulation… read more here.
Keywords: dengue; coagulation; downregulation; coagulation factors ... See more keywords